Bystander Host Cell Killing Effects of <named-content content-type="genus-species">Clostridium perfringens</named-content> Enterotoxin
ABSTRACT Clostridium perfringens enterotoxin (CPE) binds to claudin receptors, e.g., claudin-4, and then forms a pore that triggers cell death. Pure cultures of host cells that do not express claudin receptors, e.g., fibroblasts, are unaffected by pathophysiologically relevant CPE concentrations in...
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Main Authors: | Archana Shrestha, Matthew R. Hendricks, Jennifer M. Bomberger, Bruce A. McClane |
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Format: | article |
Language: | EN |
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American Society for Microbiology
2016
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Online Access: | https://doaj.org/article/de0a0e4ae92f4adba6bf1dd16c8066e2 |
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