Bystander Host Cell Killing Effects of <named-content content-type="genus-species">Clostridium perfringens</named-content> Enterotoxin

ABSTRACT Clostridium perfringens enterotoxin (CPE) binds to claudin receptors, e.g., claudin-4, and then forms a pore that triggers cell death. Pure cultures of host cells that do not express claudin receptors, e.g., fibroblasts, are unaffected by pathophysiologically relevant CPE concentrations in...

Full description

Saved in:
Bibliographic Details
Main Authors: Archana Shrestha, Matthew R. Hendricks, Jennifer M. Bomberger, Bruce A. McClane
Format: article
Language:EN
Published: American Society for Microbiology 2016
Subjects:
Online Access:https://doaj.org/article/de0a0e4ae92f4adba6bf1dd16c8066e2
Tags: Add Tag
No Tags, Be the first to tag this record!