Molecular mechanisms of the CdnG-Cap5 antiphage defense system employing 3′,2′-cGAMP as the second messenger

Many bacterial cyclic-oligonucleotide-based antiphage signaling systems (CBASS) employ effectors with SAVED domains. Here, the authors present a biochemical and structural characterization of two such CBASS, providing mechanistic insights into bacterial antiphage defense.

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Bibliographic Details
Main Authors: Shirin Fatma, Arpita Chakravarti, Xuankun Zeng, Raven H. Huang
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/de1e461a293446d0a6357b4dd12aedbc
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