Targeting MET in cancer therapy
MET encodes a receptor tyrosine kinase c-MET for hepatocyte growth factor (HGF). The specific combination of c-MET and HGF activates downstream signaling pathways to trigger cell migration, proliferation, and angiogenesis. MET exon 14 alterations and MET gene amplification play a critical role in th...
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| Main Authors: | , |
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| Format: | article |
| Language: | EN |
| Published: |
KeAi Communications Co., Ltd.
2017
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| Subjects: | |
| Online Access: | https://doaj.org/article/de222e61f8fd42a8a74c780b8dd370cb |
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