Maternal aryl hydrocarbon receptor activation protects newborns against necrotizing enterocolitis

Necrotizing enterocolitis (NEC) is a disease of prematurity requiring Toll-like receptor 4 (TLR4) activation on the gut epithelium. Here the authors show that the aryl hydrocarbon receptor (AHR) mediates NEC pathogenesis via effects on TLR4, and that supplementing the diet with AHR ligands during pr...

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Autores principales: Peng Lu, Yukihiro Yamaguchi, William B. Fulton, Sanxia Wang, Qinjie Zhou, Hongpeng Jia, Mark L. Kovler, Andres Gonzalez Salazar, Maame Sampah, Thomas Prindle, Peter Wipf, Chhinder P. Sodhi, David J. Hackam
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/de31495f0c8949b19339b71ff987a273
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