Preparation and characterization of a novel composite membrane of natural silk fiber/nano-hydroxyapatite/chitosan for guided bone tissue regeneration

Natural silk fiber (SF) was introduced into the chitosan/nano-hydroxyapatite (CS/n-HA) system to fabricate a novel guided bone tissue regeneration (GBR) membrane. The effect of different treatment methods (degummed, un-degummed, or dissolved SF) and different contents of SF on the properties of the...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Tang Shuo, Wang Weijia
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	natural polymer silk fiber biomaterials degradation guided bone tissue regeneration membrane Polymers and polymer manufacture TP1080-1185
Acceso en línea:	https://doaj.org/article/de3b1563cf5e4755a26b8cc270f4b67d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:de3b1563cf5e4755a26b8cc270f4b67d
record_format	dspace
spelling	oai:doaj.org-article:de3b1563cf5e4755a26b8cc270f4b67d2021-12-05T14:10:48ZPreparation and characterization of a novel composite membrane of natural silk fiber/nano-hydroxyapatite/chitosan for guided bone tissue regeneration1618-722910.1515/epoly-2021-0068https://doaj.org/article/de3b1563cf5e4755a26b8cc270f4b67d2021-09-01T00:00:00Zhttps://doi.org/10.1515/epoly-2021-0068https://doaj.org/toc/1618-7229Natural silk fiber (SF) was introduced into the chitosan/nano-hydroxyapatite (CS/n-HA) system to fabricate a novel guided bone tissue regeneration (GBR) membrane. The effect of different treatment methods (degummed, un-degummed, or dissolved SF) and different contents of SF on the properties of the CS/n-HA composite membrane was investigated. Results demonstrated that the degummed SF/CS/n-HA composite membrane with a weight ratio of 2:6:2 possessed the highest mechanical strength, where SF supported the composite membrane as a skeleton frame in the form of primeval state, while the un-degummed SF and dissolved SF had weaker reinforce effect due to the poor interface or poor interaction between SF and CS, and the dissolved SF/CS/n-HA composite membrane displayed the fastest degradation. However, the three SF could all improve the cell biocompatibility of the CS/n-HA composite membrane. Conclusively, the study revealed that degummed SF could in situ reinforce the CS/n-HA composite membrane with a simple and green processing method, which would provide an important guidance significant to develop a novel GBR membrane.Tang ShuoWang WeijiaDe Gruyterarticlenatural polymersilk fiberbiomaterialsdegradationguided bone tissue regeneration membranePolymers and polymer manufactureTP1080-1185ENe-Polymers, Vol 21, Iss 1, Pp 671-680 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	natural polymer silk fiber biomaterials degradation guided bone tissue regeneration membrane Polymers and polymer manufacture TP1080-1185
spellingShingle	natural polymer silk fiber biomaterials degradation guided bone tissue regeneration membrane Polymers and polymer manufacture TP1080-1185 Tang Shuo Wang Weijia Preparation and characterization of a novel composite membrane of natural silk fiber/nano-hydroxyapatite/chitosan for guided bone tissue regeneration
description	Natural silk fiber (SF) was introduced into the chitosan/nano-hydroxyapatite (CS/n-HA) system to fabricate a novel guided bone tissue regeneration (GBR) membrane. The effect of different treatment methods (degummed, un-degummed, or dissolved SF) and different contents of SF on the properties of the CS/n-HA composite membrane was investigated. Results demonstrated that the degummed SF/CS/n-HA composite membrane with a weight ratio of 2:6:2 possessed the highest mechanical strength, where SF supported the composite membrane as a skeleton frame in the form of primeval state, while the un-degummed SF and dissolved SF had weaker reinforce effect due to the poor interface or poor interaction between SF and CS, and the dissolved SF/CS/n-HA composite membrane displayed the fastest degradation. However, the three SF could all improve the cell biocompatibility of the CS/n-HA composite membrane. Conclusively, the study revealed that degummed SF could in situ reinforce the CS/n-HA composite membrane with a simple and green processing method, which would provide an important guidance significant to develop a novel GBR membrane.
format	article
author	Tang Shuo Wang Weijia
author_facet	Tang Shuo Wang Weijia
author_sort	Tang Shuo
title	Preparation and characterization of a novel composite membrane of natural silk fiber/nano-hydroxyapatite/chitosan for guided bone tissue regeneration
title_short	Preparation and characterization of a novel composite membrane of natural silk fiber/nano-hydroxyapatite/chitosan for guided bone tissue regeneration
title_full	Preparation and characterization of a novel composite membrane of natural silk fiber/nano-hydroxyapatite/chitosan for guided bone tissue regeneration
title_fullStr	Preparation and characterization of a novel composite membrane of natural silk fiber/nano-hydroxyapatite/chitosan for guided bone tissue regeneration
title_full_unstemmed	Preparation and characterization of a novel composite membrane of natural silk fiber/nano-hydroxyapatite/chitosan for guided bone tissue regeneration
title_sort	preparation and characterization of a novel composite membrane of natural silk fiber/nano-hydroxyapatite/chitosan for guided bone tissue regeneration
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/de3b1563cf5e4755a26b8cc270f4b67d
work_keys_str_mv	AT tangshuo preparationandcharacterizationofanovelcompositemembraneofnaturalsilkfibernanohydroxyapatitechitosanforguidedbonetissueregeneration AT wangweijia preparationandcharacterizationofanovelcompositemembraneofnaturalsilkfibernanohydroxyapatitechitosanforguidedbonetissueregeneration
_version_	1718371748229939200

Preparation and characterization of a novel composite membrane of natural silk fiber/nano-hydroxyapatite/chitosan for guided bone tissue regeneration

Ejemplares similares