Development of an immunodeficient pig model allowing long-term accommodation of artificial human vascular tubes

The development of tissue-engineered vascular grafts heavily relies on the availability of large animal models that allow long-term assessment of graft patency. Here Itoh et al. propose a novel model of immunodeficient pigs that allows long-term accommodation of human cell-derived three-dimensional...

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Autores principales: Manabu Itoh, Yosuke Mukae, Takahiro Kitsuka, Kenichi Arai, Anna Nakamura, Kazuyoshi Uchihashi, Shuji Toda, Kumika Matsubayashi, Jun-ichi Oyama, Koichi Node, Daisuke Kami, Satoshi Gojo, Shigeki Morita, Takahiro Nishida, Koichi Nakayama, Eiji Kobayashi
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/de4bffbba1024a2b83670ad554c1c7af
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spelling oai:doaj.org-article:de4bffbba1024a2b83670ad554c1c7af2021-12-02T15:35:55ZDevelopment of an immunodeficient pig model allowing long-term accommodation of artificial human vascular tubes10.1038/s41467-019-10107-12041-1723https://doaj.org/article/de4bffbba1024a2b83670ad554c1c7af2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10107-1https://doaj.org/toc/2041-1723The development of tissue-engineered vascular grafts heavily relies on the availability of large animal models that allow long-term assessment of graft patency. Here Itoh et al. propose a novel model of immunodeficient pigs that allows long-term accommodation of human cell-derived three-dimensional bioprinted vascular tubes.Manabu ItohYosuke MukaeTakahiro KitsukaKenichi AraiAnna NakamuraKazuyoshi UchihashiShuji TodaKumika MatsubayashiJun-ichi OyamaKoichi NodeDaisuke KamiSatoshi GojoShigeki MoritaTakahiro NishidaKoichi NakayamaEiji KobayashiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Manabu Itoh
Yosuke Mukae
Takahiro Kitsuka
Kenichi Arai
Anna Nakamura
Kazuyoshi Uchihashi
Shuji Toda
Kumika Matsubayashi
Jun-ichi Oyama
Koichi Node
Daisuke Kami
Satoshi Gojo
Shigeki Morita
Takahiro Nishida
Koichi Nakayama
Eiji Kobayashi
Development of an immunodeficient pig model allowing long-term accommodation of artificial human vascular tubes
description The development of tissue-engineered vascular grafts heavily relies on the availability of large animal models that allow long-term assessment of graft patency. Here Itoh et al. propose a novel model of immunodeficient pigs that allows long-term accommodation of human cell-derived three-dimensional bioprinted vascular tubes.
format article
author Manabu Itoh
Yosuke Mukae
Takahiro Kitsuka
Kenichi Arai
Anna Nakamura
Kazuyoshi Uchihashi
Shuji Toda
Kumika Matsubayashi
Jun-ichi Oyama
Koichi Node
Daisuke Kami
Satoshi Gojo
Shigeki Morita
Takahiro Nishida
Koichi Nakayama
Eiji Kobayashi
author_facet Manabu Itoh
Yosuke Mukae
Takahiro Kitsuka
Kenichi Arai
Anna Nakamura
Kazuyoshi Uchihashi
Shuji Toda
Kumika Matsubayashi
Jun-ichi Oyama
Koichi Node
Daisuke Kami
Satoshi Gojo
Shigeki Morita
Takahiro Nishida
Koichi Nakayama
Eiji Kobayashi
author_sort Manabu Itoh
title Development of an immunodeficient pig model allowing long-term accommodation of artificial human vascular tubes
title_short Development of an immunodeficient pig model allowing long-term accommodation of artificial human vascular tubes
title_full Development of an immunodeficient pig model allowing long-term accommodation of artificial human vascular tubes
title_fullStr Development of an immunodeficient pig model allowing long-term accommodation of artificial human vascular tubes
title_full_unstemmed Development of an immunodeficient pig model allowing long-term accommodation of artificial human vascular tubes
title_sort development of an immunodeficient pig model allowing long-term accommodation of artificial human vascular tubes
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/de4bffbba1024a2b83670ad554c1c7af
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