Modeling Atrial Fibrillation using Human Embryonic Stem Cell-Derived Atrial Tissue

Modeling Atrial Fibrillation using Human Embryonic Stem Cell-Derived Atrial Tissue

Abstract Since current experimental models of Atrial Fibrillation (AF) have significant limitations, we used human embryonic stem cells (hESCs) to generate an atrial-specific tissue model of AF for pharmacologic testing. We generated atrial-like cardiomyocytes (CMs) from hESCs which preferentially e...

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Bibliographic Details
Main Authors: Zachary Laksman, Marianne Wauchop, Eric Lin, Stephanie Protze, Jeehoon Lee, Wallace Yang, Farzad Izaddoustdar, Sanam Shafaattalab, Lior Gepstein, Glen F. Tibbits, Gordon Keller, Peter H. Backx
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/de4c7f423d3d4347aaa96056d0036cc4
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