Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites
Current strategies for regulatory control of gene expression are orthogonal to the host organism mechanisms. Here the authors demonstrate an RNA aptamer controlled system integrated into native regulatory pathways in the parasite Plasmodium falciparum.
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Nature Portfolio
2016
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oai:doaj.org-article:de4f9192e8bb4c6ba4ebcaac687eed222021-12-02T16:49:40ZSynthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites10.1038/ncomms107272041-1723https://doaj.org/article/de4f9192e8bb4c6ba4ebcaac687eed222016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10727https://doaj.org/toc/2041-1723Current strategies for regulatory control of gene expression are orthogonal to the host organism mechanisms. Here the authors demonstrate an RNA aptamer controlled system integrated into native regulatory pathways in the parasite Plasmodium falciparum.Suresh M. GanesanAlejandra FallaStephen J. GoldflessArmiyaw S. NasamuJacquin C. NilesNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016) |
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Science Q Suresh M. Ganesan Alejandra Falla Stephen J. Goldfless Armiyaw S. Nasamu Jacquin C. Niles Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites |
description |
Current strategies for regulatory control of gene expression are orthogonal to the host organism mechanisms. Here the authors demonstrate an RNA aptamer controlled system integrated into native regulatory pathways in the parasite Plasmodium falciparum. |
format |
article |
author |
Suresh M. Ganesan Alejandra Falla Stephen J. Goldfless Armiyaw S. Nasamu Jacquin C. Niles |
author_facet |
Suresh M. Ganesan Alejandra Falla Stephen J. Goldfless Armiyaw S. Nasamu Jacquin C. Niles |
author_sort |
Suresh M. Ganesan |
title |
Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites |
title_short |
Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites |
title_full |
Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites |
title_fullStr |
Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites |
title_full_unstemmed |
Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites |
title_sort |
synthetic rna–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/de4f9192e8bb4c6ba4ebcaac687eed22 |
work_keys_str_mv |
AT sureshmganesan syntheticrnaproteinmodulesintegratedwithnativetranslationmechanismstocontrolgeneexpressioninmalariaparasites AT alejandrafalla syntheticrnaproteinmodulesintegratedwithnativetranslationmechanismstocontrolgeneexpressioninmalariaparasites AT stephenjgoldfless syntheticrnaproteinmodulesintegratedwithnativetranslationmechanismstocontrolgeneexpressioninmalariaparasites AT armiyawsnasamu syntheticrnaproteinmodulesintegratedwithnativetranslationmechanismstocontrolgeneexpressioninmalariaparasites AT jacquincniles syntheticrnaproteinmodulesintegratedwithnativetranslationmechanismstocontrolgeneexpressioninmalariaparasites |
_version_ |
1718383245816496128 |