Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites

Current strategies for regulatory control of gene expression are orthogonal to the host organism mechanisms. Here the authors demonstrate an RNA aptamer controlled system integrated into native regulatory pathways in the parasite Plasmodium falciparum.

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Autores principales: Suresh M. Ganesan, Alejandra Falla, Stephen J. Goldfless, Armiyaw S. Nasamu, Jacquin C. Niles
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/de4f9192e8bb4c6ba4ebcaac687eed22
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spelling oai:doaj.org-article:de4f9192e8bb4c6ba4ebcaac687eed222021-12-02T16:49:40ZSynthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites10.1038/ncomms107272041-1723https://doaj.org/article/de4f9192e8bb4c6ba4ebcaac687eed222016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10727https://doaj.org/toc/2041-1723Current strategies for regulatory control of gene expression are orthogonal to the host organism mechanisms. Here the authors demonstrate an RNA aptamer controlled system integrated into native regulatory pathways in the parasite Plasmodium falciparum.Suresh M. GanesanAlejandra FallaStephen J. GoldflessArmiyaw S. NasamuJacquin C. NilesNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Suresh M. Ganesan
Alejandra Falla
Stephen J. Goldfless
Armiyaw S. Nasamu
Jacquin C. Niles
Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites
description Current strategies for regulatory control of gene expression are orthogonal to the host organism mechanisms. Here the authors demonstrate an RNA aptamer controlled system integrated into native regulatory pathways in the parasite Plasmodium falciparum.
format article
author Suresh M. Ganesan
Alejandra Falla
Stephen J. Goldfless
Armiyaw S. Nasamu
Jacquin C. Niles
author_facet Suresh M. Ganesan
Alejandra Falla
Stephen J. Goldfless
Armiyaw S. Nasamu
Jacquin C. Niles
author_sort Suresh M. Ganesan
title Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites
title_short Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites
title_full Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites
title_fullStr Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites
title_full_unstemmed Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites
title_sort synthetic rna–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/de4f9192e8bb4c6ba4ebcaac687eed22
work_keys_str_mv AT sureshmganesan syntheticrnaproteinmodulesintegratedwithnativetranslationmechanismstocontrolgeneexpressioninmalariaparasites
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AT stephenjgoldfless syntheticrnaproteinmodulesintegratedwithnativetranslationmechanismstocontrolgeneexpressioninmalariaparasites
AT armiyawsnasamu syntheticrnaproteinmodulesintegratedwithnativetranslationmechanismstocontrolgeneexpressioninmalariaparasites
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