The climatic and genetic heritage of Italian goat breeds with genomic SNP data
Abstract Local adaptation of animals to the environment can abruptly become a burden when faced with rapid climatic changes such as those foreseen for the Italian peninsula over the next 70 years. Our study investigates the genetic structure of the Italian goat populations and links it with the envi...
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Nature Portfolio
2021
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oai:doaj.org-article:de5f9312384a4e86a4e3b1dd0ccf3ee22021-12-02T15:49:50ZThe climatic and genetic heritage of Italian goat breeds with genomic SNP data10.1038/s41598-021-89900-22045-2322https://doaj.org/article/de5f9312384a4e86a4e3b1dd0ccf3ee22021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-89900-2https://doaj.org/toc/2045-2322Abstract Local adaptation of animals to the environment can abruptly become a burden when faced with rapid climatic changes such as those foreseen for the Italian peninsula over the next 70 years. Our study investigates the genetic structure of the Italian goat populations and links it with the environment and how genetics might evolve over the next 50 years. We used one of the largest national datasets including > 1000 goats from 33 populations across the Italian peninsula collected by the Italian Goat Consortium and genotyped with over 50 k markers. Our results showed that Italian goats can be discriminated in three groups reflective of the Italian geography and its geo-political situation preceding the country unification around two centuries ago. We leveraged the remarkable genetic and geographical diversity of the Italian goat populations and performed landscape genomics analysis to disentangle the relationship between genotype and environment, finding 64 SNPs intercepting genomic regions linked to growth, circadian rhythm, fertility, and inflammatory response. Lastly, we calculated the hypothetical future genotypic frequencies of the most relevant SNPs identified through landscape genomics to evaluate their long-term effect on the genetic structure of the Italian goat populations. Our results provide an insight into the past and the future of the Italian local goat populations, helping the institutions in defining new conservation strategy plans that could preserve their diversity and their link to local realities challenged by climate change.Matteo CortellariMario BarbatoAndrea TalentiArianna BiondaAntonello CartaRoberta CiampoliniElena CianiAlessandra CrisàStefano FrattiniEmiliano LasagnaDonata MarlettaSalvatore MastrangeloAlessio NegroEttore RandiFrancesca M. SartiStefano SartoreDominga SogliaLuigi LiottaAlessandra StellaPaolo Ajmone-MarsanFabio PillaLicia ColliPaola CrepaldiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021) |
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Medicine R Science Q Matteo Cortellari Mario Barbato Andrea Talenti Arianna Bionda Antonello Carta Roberta Ciampolini Elena Ciani Alessandra Crisà Stefano Frattini Emiliano Lasagna Donata Marletta Salvatore Mastrangelo Alessio Negro Ettore Randi Francesca M. Sarti Stefano Sartore Dominga Soglia Luigi Liotta Alessandra Stella Paolo Ajmone-Marsan Fabio Pilla Licia Colli Paola Crepaldi The climatic and genetic heritage of Italian goat breeds with genomic SNP data |
| description |
Abstract Local adaptation of animals to the environment can abruptly become a burden when faced with rapid climatic changes such as those foreseen for the Italian peninsula over the next 70 years. Our study investigates the genetic structure of the Italian goat populations and links it with the environment and how genetics might evolve over the next 50 years. We used one of the largest national datasets including > 1000 goats from 33 populations across the Italian peninsula collected by the Italian Goat Consortium and genotyped with over 50 k markers. Our results showed that Italian goats can be discriminated in three groups reflective of the Italian geography and its geo-political situation preceding the country unification around two centuries ago. We leveraged the remarkable genetic and geographical diversity of the Italian goat populations and performed landscape genomics analysis to disentangle the relationship between genotype and environment, finding 64 SNPs intercepting genomic regions linked to growth, circadian rhythm, fertility, and inflammatory response. Lastly, we calculated the hypothetical future genotypic frequencies of the most relevant SNPs identified through landscape genomics to evaluate their long-term effect on the genetic structure of the Italian goat populations. Our results provide an insight into the past and the future of the Italian local goat populations, helping the institutions in defining new conservation strategy plans that could preserve their diversity and their link to local realities challenged by climate change. |
| format |
article |
| author |
Matteo Cortellari Mario Barbato Andrea Talenti Arianna Bionda Antonello Carta Roberta Ciampolini Elena Ciani Alessandra Crisà Stefano Frattini Emiliano Lasagna Donata Marletta Salvatore Mastrangelo Alessio Negro Ettore Randi Francesca M. Sarti Stefano Sartore Dominga Soglia Luigi Liotta Alessandra Stella Paolo Ajmone-Marsan Fabio Pilla Licia Colli Paola Crepaldi |
| author_facet |
Matteo Cortellari Mario Barbato Andrea Talenti Arianna Bionda Antonello Carta Roberta Ciampolini Elena Ciani Alessandra Crisà Stefano Frattini Emiliano Lasagna Donata Marletta Salvatore Mastrangelo Alessio Negro Ettore Randi Francesca M. Sarti Stefano Sartore Dominga Soglia Luigi Liotta Alessandra Stella Paolo Ajmone-Marsan Fabio Pilla Licia Colli Paola Crepaldi |
| author_sort |
Matteo Cortellari |
| title |
The climatic and genetic heritage of Italian goat breeds with genomic SNP data |
| title_short |
The climatic and genetic heritage of Italian goat breeds with genomic SNP data |
| title_full |
The climatic and genetic heritage of Italian goat breeds with genomic SNP data |
| title_fullStr |
The climatic and genetic heritage of Italian goat breeds with genomic SNP data |
| title_full_unstemmed |
The climatic and genetic heritage of Italian goat breeds with genomic SNP data |
| title_sort |
climatic and genetic heritage of italian goat breeds with genomic snp data |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/de5f9312384a4e86a4e3b1dd0ccf3ee2 |
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