The FlgN chaperone activates the Na+-driven engine of the Salmonella flagellar protein export apparatus

Minamino et al. report that the bacterial FlgN chaperone acts as a switch to activate a backup mechanism for H+-coupled flagellar protein export by interacting with FlhAC to activate the Na+-driven export engine. The proposed mechanism helps to explain how bacteria can maintain flagellar protein exp...

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Autores principales:	Tohru Minamino, Miki Kinoshita, Yusuke V. Morimoto, Keiichi Namba
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/de61e2e8ffbe45fdaa035216e7c70a89
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spelling	oai:doaj.org-article:de61e2e8ffbe45fdaa035216e7c70a892021-12-02T13:15:51ZThe FlgN chaperone activates the Na+-driven engine of the Salmonella flagellar protein export apparatus10.1038/s42003-021-01865-02399-3642https://doaj.org/article/de61e2e8ffbe45fdaa035216e7c70a892021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01865-0https://doaj.org/toc/2399-3642Minamino et al. report that the bacterial FlgN chaperone acts as a switch to activate a backup mechanism for H+-coupled flagellar protein export by interacting with FlhAC to activate the Na+-driven export engine. The proposed mechanism helps to explain how bacteria can maintain flagellar protein export when the ATPase complex export machinery becomes non-functional.Tohru MinaminoMiki KinoshitaYusuke V. MorimotoKeiichi NambaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Tohru Minamino Miki Kinoshita Yusuke V. Morimoto Keiichi Namba The FlgN chaperone activates the Na+-driven engine of the Salmonella flagellar protein export apparatus
description	Minamino et al. report that the bacterial FlgN chaperone acts as a switch to activate a backup mechanism for H+-coupled flagellar protein export by interacting with FlhAC to activate the Na+-driven export engine. The proposed mechanism helps to explain how bacteria can maintain flagellar protein export when the ATPase complex export machinery becomes non-functional.
format	article
author	Tohru Minamino Miki Kinoshita Yusuke V. Morimoto Keiichi Namba
author_facet	Tohru Minamino Miki Kinoshita Yusuke V. Morimoto Keiichi Namba
author_sort	Tohru Minamino
title	The FlgN chaperone activates the Na+-driven engine of the Salmonella flagellar protein export apparatus
title_short	The FlgN chaperone activates the Na+-driven engine of the Salmonella flagellar protein export apparatus
title_full	The FlgN chaperone activates the Na+-driven engine of the Salmonella flagellar protein export apparatus
title_fullStr	The FlgN chaperone activates the Na+-driven engine of the Salmonella flagellar protein export apparatus
title_full_unstemmed	The FlgN chaperone activates the Na+-driven engine of the Salmonella flagellar protein export apparatus
title_sort	flgn chaperone activates the na+-driven engine of the salmonella flagellar protein export apparatus
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/de61e2e8ffbe45fdaa035216e7c70a89
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The FlgN chaperone activates the Na+-driven engine of the Salmonella flagellar protein export apparatus

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