Application of Box-Behnken designs in parameters optimization of differential pulse anodic stripping voltammetry for lead(II) determination in two electrolytes

Abstract Box-Behnken design was advantageous to parameters optimization of differential pulse anodic stripping voltammetry (DPASV) for the analysis of lead(II) with its high efficiency and accuracy. Five Box-Behnken designs were designed and conducted in the electrolyte of 0.1 mol/L acetate buffer a...

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Autores principales:	Xiao-Lan Yu, Yong He
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/de6268ff71c549dba43106cb2d6597a4
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spelling	oai:doaj.org-article:de6268ff71c549dba43106cb2d6597a42021-12-02T16:06:00ZApplication of Box-Behnken designs in parameters optimization of differential pulse anodic stripping voltammetry for lead(II) determination in two electrolytes10.1038/s41598-017-03030-22045-2322https://doaj.org/article/de6268ff71c549dba43106cb2d6597a42017-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-03030-2https://doaj.org/toc/2045-2322Abstract Box-Behnken design was advantageous to parameters optimization of differential pulse anodic stripping voltammetry (DPASV) for the analysis of lead(II) with its high efficiency and accuracy. Five Box-Behnken designs were designed and conducted in the electrolyte of 0.1 mol/L acetate buffer and 0.1 mol/L HCl without the removal of oxygen. Significant parameters and interactions in each electrolyte were found (P-value < 0.05) and their quantitative effects on lead(II) determination were classified into two categories, linear and quadratic. Though significant parameters and interactions were not similar in different kinds of electrolytes, characteristic parameters of differential pulse voltammetry, which were pulse amplitude, pulse width and interval time, were found significant in both electrolytes. After optimization, peak currents and relative standard deviation at 20 μg/L along with detection limits in both electrolytes were superior than before. With the lower detection limit and R.S.D., 0.1 mol/L HCl was a better choice for electrolytes in this work. Meanwhile, with the combination of parameters optimization and background subtraction, the interference of dissolved oxygen for lead(II) determination was eliminated. It was important and necessary to apply Box-Behnken designs in parameters optimization of DPASV for lead(II) determination regardless of the electrolyte kinds.Xiao-Lan YuYong HeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Xiao-Lan Yu Yong He Application of Box-Behnken designs in parameters optimization of differential pulse anodic stripping voltammetry for lead(II) determination in two electrolytes
description	Abstract Box-Behnken design was advantageous to parameters optimization of differential pulse anodic stripping voltammetry (DPASV) for the analysis of lead(II) with its high efficiency and accuracy. Five Box-Behnken designs were designed and conducted in the electrolyte of 0.1 mol/L acetate buffer and 0.1 mol/L HCl without the removal of oxygen. Significant parameters and interactions in each electrolyte were found (P-value < 0.05) and their quantitative effects on lead(II) determination were classified into two categories, linear and quadratic. Though significant parameters and interactions were not similar in different kinds of electrolytes, characteristic parameters of differential pulse voltammetry, which were pulse amplitude, pulse width and interval time, were found significant in both electrolytes. After optimization, peak currents and relative standard deviation at 20 μg/L along with detection limits in both electrolytes were superior than before. With the lower detection limit and R.S.D., 0.1 mol/L HCl was a better choice for electrolytes in this work. Meanwhile, with the combination of parameters optimization and background subtraction, the interference of dissolved oxygen for lead(II) determination was eliminated. It was important and necessary to apply Box-Behnken designs in parameters optimization of DPASV for lead(II) determination regardless of the electrolyte kinds.
format	article
author	Xiao-Lan Yu Yong He
author_facet	Xiao-Lan Yu Yong He
author_sort	Xiao-Lan Yu
title	Application of Box-Behnken designs in parameters optimization of differential pulse anodic stripping voltammetry for lead(II) determination in two electrolytes
title_short	Application of Box-Behnken designs in parameters optimization of differential pulse anodic stripping voltammetry for lead(II) determination in two electrolytes
title_full	Application of Box-Behnken designs in parameters optimization of differential pulse anodic stripping voltammetry for lead(II) determination in two electrolytes
title_fullStr	Application of Box-Behnken designs in parameters optimization of differential pulse anodic stripping voltammetry for lead(II) determination in two electrolytes
title_full_unstemmed	Application of Box-Behnken designs in parameters optimization of differential pulse anodic stripping voltammetry for lead(II) determination in two electrolytes
title_sort	application of box-behnken designs in parameters optimization of differential pulse anodic stripping voltammetry for lead(ii) determination in two electrolytes
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/de6268ff71c549dba43106cb2d6597a4
work_keys_str_mv	AT xiaolanyu applicationofboxbehnkendesignsinparametersoptimizationofdifferentialpulseanodicstrippingvoltammetryforleadiideterminationintwoelectrolytes AT yonghe applicationofboxbehnkendesignsinparametersoptimizationofdifferentialpulseanodicstrippingvoltammetryforleadiideterminationintwoelectrolytes
_version_	1718385179348697088

Application of Box-Behnken designs in parameters optimization of differential pulse anodic stripping voltammetry for lead(II) determination in two electrolytes

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