An inter-day assessment of the ABC parameters in the evaluation of progressive keratoconus

Abstract The progression of keratoconus is commonly determined by comparing the results of corneal tomographic measurements on different occasions. However, investigations on the repeatability of measurements are commonly performed within the same day, thus not taking the inter-day variation into ac...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ingemar Gustafsson, Tove Faxén, André Vicente, Anders Bergström, Anders Ivarsen, Jesper Østergaard Hjortdal
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/de63dbbd3ac842789586de16e901895a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:de63dbbd3ac842789586de16e901895a
record_format	dspace
spelling	oai:doaj.org-article:de63dbbd3ac842789586de16e901895a2021-12-02T18:49:36ZAn inter-day assessment of the ABC parameters in the evaluation of progressive keratoconus10.1038/s41598-021-95503-82045-2322https://doaj.org/article/de63dbbd3ac842789586de16e901895a2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-95503-8https://doaj.org/toc/2045-2322Abstract The progression of keratoconus is commonly determined by comparing the results of corneal tomographic measurements on different occasions. However, investigations on the repeatability of measurements are commonly performed within the same day, thus not taking the inter-day variation into account. The effect of keratoconus disease severity on the measurement error is also seldom considered. In this post hoc investigation, the parameters A, B and C in the Belin ABCD Progression Display were evaluated in relation to disease severity in intra-day and inter-day measurements. Four consecutive measurements were performed on 61 patients with keratoconus on the same day (intra-day). In another cohort, four consecutive measurements were obtained and then repeated 3 days later in 25 patients with keratoconus and 25 healthy controls (inter-day). The results suggest that the diagnosis of disease progression would benefit from inter-day measurements, and the stratification of the parameters A and C according to disease severity. It is also recommended that tomographic systems such as the Pentacam HR be modified to allow the comparison of both single measurements and the mean of replicate measurements of the parameters used in the assessment of progression of keratoconus.Ingemar GustafssonTove FaxénAndré VicenteAnders BergströmAnders IvarsenJesper Østergaard HjortdalNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ingemar Gustafsson Tove Faxén André Vicente Anders Bergström Anders Ivarsen Jesper Østergaard Hjortdal An inter-day assessment of the ABC parameters in the evaluation of progressive keratoconus
description	Abstract The progression of keratoconus is commonly determined by comparing the results of corneal tomographic measurements on different occasions. However, investigations on the repeatability of measurements are commonly performed within the same day, thus not taking the inter-day variation into account. The effect of keratoconus disease severity on the measurement error is also seldom considered. In this post hoc investigation, the parameters A, B and C in the Belin ABCD Progression Display were evaluated in relation to disease severity in intra-day and inter-day measurements. Four consecutive measurements were performed on 61 patients with keratoconus on the same day (intra-day). In another cohort, four consecutive measurements were obtained and then repeated 3 days later in 25 patients with keratoconus and 25 healthy controls (inter-day). The results suggest that the diagnosis of disease progression would benefit from inter-day measurements, and the stratification of the parameters A and C according to disease severity. It is also recommended that tomographic systems such as the Pentacam HR be modified to allow the comparison of both single measurements and the mean of replicate measurements of the parameters used in the assessment of progression of keratoconus.
format	article
author	Ingemar Gustafsson Tove Faxén André Vicente Anders Bergström Anders Ivarsen Jesper Østergaard Hjortdal
author_facet	Ingemar Gustafsson Tove Faxén André Vicente Anders Bergström Anders Ivarsen Jesper Østergaard Hjortdal
author_sort	Ingemar Gustafsson
title	An inter-day assessment of the ABC parameters in the evaluation of progressive keratoconus
title_short	An inter-day assessment of the ABC parameters in the evaluation of progressive keratoconus
title_full	An inter-day assessment of the ABC parameters in the evaluation of progressive keratoconus
title_fullStr	An inter-day assessment of the ABC parameters in the evaluation of progressive keratoconus
title_full_unstemmed	An inter-day assessment of the ABC parameters in the evaluation of progressive keratoconus
title_sort	inter-day assessment of the abc parameters in the evaluation of progressive keratoconus
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/de63dbbd3ac842789586de16e901895a
work_keys_str_mv	AT ingemargustafsson aninterdayassessmentoftheabcparametersintheevaluationofprogressivekeratoconus AT tovefaxen aninterdayassessmentoftheabcparametersintheevaluationofprogressivekeratoconus AT andrevicente aninterdayassessmentoftheabcparametersintheevaluationofprogressivekeratoconus AT andersbergstrom aninterdayassessmentoftheabcparametersintheevaluationofprogressivekeratoconus AT andersivarsen aninterdayassessmentoftheabcparametersintheevaluationofprogressivekeratoconus AT jesperøstergaardhjortdal aninterdayassessmentoftheabcparametersintheevaluationofprogressivekeratoconus AT ingemargustafsson interdayassessmentoftheabcparametersintheevaluationofprogressivekeratoconus AT tovefaxen interdayassessmentoftheabcparametersintheevaluationofprogressivekeratoconus AT andrevicente interdayassessmentoftheabcparametersintheevaluationofprogressivekeratoconus AT andersbergstrom interdayassessmentoftheabcparametersintheevaluationofprogressivekeratoconus AT andersivarsen interdayassessmentoftheabcparametersintheevaluationofprogressivekeratoconus AT jesperøstergaardhjortdal interdayassessmentoftheabcparametersintheevaluationofprogressivekeratoconus
_version_	1718377595780726784

An inter-day assessment of the ABC parameters in the evaluation of progressive keratoconus

Ejemplares similares