Cerebellar disruption impairs working memory during evidence accumulation

Disruption of cerebellar activity impairs working memory during evidence accumulation in mice. Here, the authors show that optogenetic perturbation of Purkinje cell activity disrupts the accurate accumulation of somatosensory information in working memory during perceptual decision-making.

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Autores principales:	Ben Deverett, Mikhail Kislin, David W. Tank, Samuel S.-H. Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/de6e44beedb043dfbf9f02ffc63f0b8e
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spelling	oai:doaj.org-article:de6e44beedb043dfbf9f02ffc63f0b8e2021-12-02T14:35:56ZCerebellar disruption impairs working memory during evidence accumulation10.1038/s41467-019-11050-x2041-1723https://doaj.org/article/de6e44beedb043dfbf9f02ffc63f0b8e2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11050-xhttps://doaj.org/toc/2041-1723Disruption of cerebellar activity impairs working memory during evidence accumulation in mice. Here, the authors show that optogenetic perturbation of Purkinje cell activity disrupts the accurate accumulation of somatosensory information in working memory during perceptual decision-making.Ben DeverettMikhail KislinDavid W. TankSamuel S.-H. WangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ben Deverett Mikhail Kislin David W. Tank Samuel S.-H. Wang Cerebellar disruption impairs working memory during evidence accumulation
description	Disruption of cerebellar activity impairs working memory during evidence accumulation in mice. Here, the authors show that optogenetic perturbation of Purkinje cell activity disrupts the accurate accumulation of somatosensory information in working memory during perceptual decision-making.
format	article
author	Ben Deverett Mikhail Kislin David W. Tank Samuel S.-H. Wang
author_facet	Ben Deverett Mikhail Kislin David W. Tank Samuel S.-H. Wang
author_sort	Ben Deverett
title	Cerebellar disruption impairs working memory during evidence accumulation
title_short	Cerebellar disruption impairs working memory during evidence accumulation
title_full	Cerebellar disruption impairs working memory during evidence accumulation
title_fullStr	Cerebellar disruption impairs working memory during evidence accumulation
title_full_unstemmed	Cerebellar disruption impairs working memory during evidence accumulation
title_sort	cerebellar disruption impairs working memory during evidence accumulation
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/de6e44beedb043dfbf9f02ffc63f0b8e
work_keys_str_mv	AT bendeverett cerebellardisruptionimpairsworkingmemoryduringevidenceaccumulation AT mikhailkislin cerebellardisruptionimpairsworkingmemoryduringevidenceaccumulation AT davidwtank cerebellardisruptionimpairsworkingmemoryduringevidenceaccumulation AT samuelshwang cerebellardisruptionimpairsworkingmemoryduringevidenceaccumulation
_version_	1718391039408996352

Cerebellar disruption impairs working memory during evidence accumulation

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