IFNL4 ss469415590 variant shows similar performance to rs12979860 as predictor of response to treatment against Hepatitis C Virus genotype 1 or 4 in Caucasians.

IFNL4 ss469415590 variant shows similar performance to rs12979860 as predictor of response to treatment against Hepatitis C Virus genotype 1 or 4 in Caucasians.

<h4>Objectives</h4>The rs12979860 variant, linked to IL28B gene, predicts sustained viral response (SVR) to pegylated-interferon/ribavirin (pegIFN/RBV) therapy in Hepatitis C Virus genotype 1 or 4 (HCV-1/4)-infected patients. Recently, a functional variant, ss469415590, in linkage disequ...

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Autores principales: Luis M Real, Karin Neukam, Rocío Herrero, Josep M Guardiola, Thomas Reiberger, Antonio Rivero-Juarez, Juliana Salazar, Mattias Mandorfer, Dolores Merino, Vicente Soriano, Antonio Rivero, Juan Macías, Juan A Pineda, Antonio Caruz
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/de6f613c61a94af99f5f7688fb8f44dd
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