Halofuginone Sensitizes Lung Cancer Organoids to Cisplatin via Suppressing PI3K/AKT and MAPK Signaling Pathways
Lung cancer is the leading cause of cancer death worldwide. Cisplatin is the major DNA-damaging anticancer drug that cross-links the DNA in cancer cells, but many patients inevitably develop resistance with treatment. Identification of a cisplatin sensitizer might postpone or even reverse the develo...
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Autores principales: | Hefei Li, Yushan Zhang, Xiaomei Lan, Jianhua Yu, Changshuang Yang, Zhijian Sun, Ping Kang, Yi Han, Daping Yu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/de72a317bcf34a199a69572a0f396bee |
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