A case report of Cholinergic syndrome an unusual complication of Neostigmine administration

Background and Objective: Cholinergic syndrome (Cholinergic crisis) is an extremely dangerous complication of anti-cholinesterase drugs such as neostigmine. Isolated forearm technique (IFT) with IV injection of neostigmine is used for the evaluation of awareness, which is a deliberate problem in nar...

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Autores principales:	Z Hussain Khan, H Majedi
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2002
Materias:	cholinergic drugs cholinesterase inhibitors awareness drug interaction neostigmine Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/de74bef419be4e93a32c81c018cf3a6f
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spelling	oai:doaj.org-article:de74bef419be4e93a32c81c018cf3a6f2021-11-10T09:19:41ZA case report of Cholinergic syndrome an unusual complication of Neostigmine administration1561-41072251-7170https://doaj.org/article/de74bef419be4e93a32c81c018cf3a6f2002-07-01T00:00:00Zhttp://jbums.org/article-1-2826-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and Objective: Cholinergic syndrome (Cholinergic crisis) is an extremely dangerous complication of anti-cholinesterase drugs such as neostigmine. Isolated forearm technique (IFT) with IV injection of neostigmine is used for the evaluation of awareness, which is a deliberate problem in narcotic based anesthesia. This method is used for evaluation of ischemia of the anterior spinal artery and weakness of upper extremity motor after operation of cervical spines. Case: The case was a 43-year-old woman with dislocated C1-C2 fracture who was candidated for cervical spines surgery. After IFT, induction of anesthesia and tracheal intubation (Muscarinic and nicotinic) Cholinergic symptoms of crisis were developed that the cause of this presentation was IFT with injection of neostigmine. Conclusion: Since, the evaluation of awareness is not so predictable by IFT procedure, it is recommended to use other modern techniques such as bispectral index, nerve stimulators and evoked potentials.Z Hussain KhanH MajediBabol University of Medical Sciencesarticlecholinergic drugscholinesterase inhibitorsawarenessdrug interactionneostigmineMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 4, Iss 3, Pp 67-72 (2002)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	cholinergic drugs cholinesterase inhibitors awareness drug interaction neostigmine Medicine R Medicine (General) R5-920
spellingShingle	cholinergic drugs cholinesterase inhibitors awareness drug interaction neostigmine Medicine R Medicine (General) R5-920 Z Hussain Khan H Majedi A case report of Cholinergic syndrome an unusual complication of Neostigmine administration
description	Background and Objective: Cholinergic syndrome (Cholinergic crisis) is an extremely dangerous complication of anti-cholinesterase drugs such as neostigmine. Isolated forearm technique (IFT) with IV injection of neostigmine is used for the evaluation of awareness, which is a deliberate problem in narcotic based anesthesia. This method is used for evaluation of ischemia of the anterior spinal artery and weakness of upper extremity motor after operation of cervical spines. Case: The case was a 43-year-old woman with dislocated C1-C2 fracture who was candidated for cervical spines surgery. After IFT, induction of anesthesia and tracheal intubation (Muscarinic and nicotinic) Cholinergic symptoms of crisis were developed that the cause of this presentation was IFT with injection of neostigmine. Conclusion: Since, the evaluation of awareness is not so predictable by IFT procedure, it is recommended to use other modern techniques such as bispectral index, nerve stimulators and evoked potentials.
format	article
author	Z Hussain Khan H Majedi
author_facet	Z Hussain Khan H Majedi
author_sort	Z Hussain Khan
title	A case report of Cholinergic syndrome an unusual complication of Neostigmine administration
title_short	A case report of Cholinergic syndrome an unusual complication of Neostigmine administration
title_full	A case report of Cholinergic syndrome an unusual complication of Neostigmine administration
title_fullStr	A case report of Cholinergic syndrome an unusual complication of Neostigmine administration
title_full_unstemmed	A case report of Cholinergic syndrome an unusual complication of Neostigmine administration
title_sort	case report of cholinergic syndrome an unusual complication of neostigmine administration
publisher	Babol University of Medical Sciences
publishDate	2002
url	https://doaj.org/article/de74bef419be4e93a32c81c018cf3a6f
work_keys_str_mv	AT zhussainkhan acasereportofcholinergicsyndromeanunusualcomplicationofneostigmineadministration AT hmajedi acasereportofcholinergicsyndromeanunusualcomplicationofneostigmineadministration AT zhussainkhan casereportofcholinergicsyndromeanunusualcomplicationofneostigmineadministration AT hmajedi casereportofcholinergicsyndromeanunusualcomplicationofneostigmineadministration
_version_	1718440147630948353

A case report of Cholinergic syndrome an unusual complication of Neostigmine administration

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