Burden of puerperal sepsis and its associated factors in Ethiopia: a systematic review and meta-analysis

Abstract Background Puerperal sepsis is a genital tract infection that can occur from amniotic fluid rupture to six weeks after birth. Maternal complication associated with puerperal sepsis includes prolonged hospital stay, septicemia, disseminated intravascular coagulation, pelvic inflammatory dise...

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Autores principales:	Abenezer Melkie, Enyew Dagnew
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Burden Puerperal sepsis Associated factors Ethiopia Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/de7647a983934278818b1a4e569290f2
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spelling	oai:doaj.org-article:de7647a983934278818b1a4e569290f22021-12-05T12:09:54ZBurden of puerperal sepsis and its associated factors in Ethiopia: a systematic review and meta-analysis10.1186/s13690-021-00732-y2049-3258https://doaj.org/article/de7647a983934278818b1a4e569290f22021-11-01T00:00:00Zhttps://doi.org/10.1186/s13690-021-00732-yhttps://doaj.org/toc/2049-3258Abstract Background Puerperal sepsis is a genital tract infection that can occur from amniotic fluid rupture to six weeks after birth. Maternal complication associated with puerperal sepsis includes prolonged hospital stay, septicemia, disseminated intravascular coagulation, pelvic inflammatory disease, infertility, and death. Even though, puerperal sepsis is the fourth leading cause of maternal morbidity and mortality in Ethiopia the overall prevalence of puerperal sepsis and its associated factors are not studied at the national stage. As a result, this systematic review and meta-analysis bring out the pooled prevalence of puerperal sepsis and its associated factors in Ethiopia. Methods A variety of data sources such as Pub Med, Web of Science, Science Direct, Embase, Google Scholar, HINARI, and Ethiopian universities online repositories were searched to identify the primary studies which were used for this systematic review and meta-analysis. The article search was conducted from February10/2021-March 10/2021. The quality of the selected primary studies was assessed using the Newcastle - Ottawa quality assessment Scale (NOS). Data extraction was done with Microsoft Excel and then exported to STATA 11 version statistical software for analysis. The Cochran (Q-test) and I2 test statistics were used to assess the heterogeneity of the studies. Publication bias was evaluated by the eggers regression test. Subgroup analysis was performed with region and sample size category. Result In this review, a total of 2222 respondents were involved from seven studies. The pooled prevalence of puerperal sepsis was 14.811% (95%CI; 8.46: 21.16; I2 = 94.2, P ≤ 0.001). Cesarean section delivery (CSD) (OR = 3.26, 95%CI: 1.90, 5.61), membrane rupture≥24 h (OR = 4.04, 95%CI: 2.54, 6.42), being multiparous mother (OR = 3.99, 95%CI: 1.82, 8.78), vaginal examination≥5 times (OR = 3.15, 95%CI: 1.17, 8.52), and anemia (OR = 5.68, 95%CI: 4.38, 7.36) were factors significantly associated with puerperal sepsis. Conclusion The prevalence of puerperal sepsis was high in Ethiopia. CSD, membrane rupture≥24 h, being multiparous mother, vaginal examination≥5, and anemia were factors associated with puerperal sepsis. Appropriate standard infection prevention techniques during CSD shall be practiced to reduce the maternal burden of puerperal sepsis. The unnecessary vaginal examination should be discouraged during the intrapartum period. Besides this, routine Iron sulfate supplementation and counsel on iron reach foods during ante partum and postpartum shall be considered for all mothers.Abenezer MelkieEnyew DagnewBMCarticleBurdenPuerperal sepsisAssociated factorsEthiopiaPublic aspects of medicineRA1-1270ENArchives of Public Health, Vol 79, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Burden Puerperal sepsis Associated factors Ethiopia Public aspects of medicine RA1-1270
spellingShingle	Burden Puerperal sepsis Associated factors Ethiopia Public aspects of medicine RA1-1270 Abenezer Melkie Enyew Dagnew Burden of puerperal sepsis and its associated factors in Ethiopia: a systematic review and meta-analysis
description	Abstract Background Puerperal sepsis is a genital tract infection that can occur from amniotic fluid rupture to six weeks after birth. Maternal complication associated with puerperal sepsis includes prolonged hospital stay, septicemia, disseminated intravascular coagulation, pelvic inflammatory disease, infertility, and death. Even though, puerperal sepsis is the fourth leading cause of maternal morbidity and mortality in Ethiopia the overall prevalence of puerperal sepsis and its associated factors are not studied at the national stage. As a result, this systematic review and meta-analysis bring out the pooled prevalence of puerperal sepsis and its associated factors in Ethiopia. Methods A variety of data sources such as Pub Med, Web of Science, Science Direct, Embase, Google Scholar, HINARI, and Ethiopian universities online repositories were searched to identify the primary studies which were used for this systematic review and meta-analysis. The article search was conducted from February10/2021-March 10/2021. The quality of the selected primary studies was assessed using the Newcastle - Ottawa quality assessment Scale (NOS). Data extraction was done with Microsoft Excel and then exported to STATA 11 version statistical software for analysis. The Cochran (Q-test) and I2 test statistics were used to assess the heterogeneity of the studies. Publication bias was evaluated by the eggers regression test. Subgroup analysis was performed with region and sample size category. Result In this review, a total of 2222 respondents were involved from seven studies. The pooled prevalence of puerperal sepsis was 14.811% (95%CI; 8.46: 21.16; I2 = 94.2, P ≤ 0.001). Cesarean section delivery (CSD) (OR = 3.26, 95%CI: 1.90, 5.61), membrane rupture≥24 h (OR = 4.04, 95%CI: 2.54, 6.42), being multiparous mother (OR = 3.99, 95%CI: 1.82, 8.78), vaginal examination≥5 times (OR = 3.15, 95%CI: 1.17, 8.52), and anemia (OR = 5.68, 95%CI: 4.38, 7.36) were factors significantly associated with puerperal sepsis. Conclusion The prevalence of puerperal sepsis was high in Ethiopia. CSD, membrane rupture≥24 h, being multiparous mother, vaginal examination≥5, and anemia were factors associated with puerperal sepsis. Appropriate standard infection prevention techniques during CSD shall be practiced to reduce the maternal burden of puerperal sepsis. The unnecessary vaginal examination should be discouraged during the intrapartum period. Besides this, routine Iron sulfate supplementation and counsel on iron reach foods during ante partum and postpartum shall be considered for all mothers.
format	article
author	Abenezer Melkie Enyew Dagnew
author_facet	Abenezer Melkie Enyew Dagnew
author_sort	Abenezer Melkie
title	Burden of puerperal sepsis and its associated factors in Ethiopia: a systematic review and meta-analysis
title_short	Burden of puerperal sepsis and its associated factors in Ethiopia: a systematic review and meta-analysis
title_full	Burden of puerperal sepsis and its associated factors in Ethiopia: a systematic review and meta-analysis
title_fullStr	Burden of puerperal sepsis and its associated factors in Ethiopia: a systematic review and meta-analysis
title_full_unstemmed	Burden of puerperal sepsis and its associated factors in Ethiopia: a systematic review and meta-analysis
title_sort	burden of puerperal sepsis and its associated factors in ethiopia: a systematic review and meta-analysis
publisher	BMC
publishDate	2021
url	https://doaj.org/article/de7647a983934278818b1a4e569290f2
work_keys_str_mv	AT abenezermelkie burdenofpuerperalsepsisanditsassociatedfactorsinethiopiaasystematicreviewandmetaanalysis AT enyewdagnew burdenofpuerperalsepsisanditsassociatedfactorsinethiopiaasystematicreviewandmetaanalysis
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Burden of puerperal sepsis and its associated factors in Ethiopia: a systematic review and meta-analysis

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