Impact of bronchiolitis guidelines publication on primary care prescriptions in the Italian pediatric population

Abstract In Italy, two clinical practice guidelines for the diagnosis and treatment of bronchiolitis were published in October 2014 and December 2015. We evaluated prescriptions for bronchiolitis in children aged 0–24 months before (December 2012–December 2014), in between (December 2014–December 20...

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Autores principales:	Elisa Barbieri, Anna Cantarutti, Sara Cavagnis, Luigi Cantarutti, Eugenio Baraldi, Carlo Giaquinto, Daniele Donà
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Diseases of the respiratory system RC705-779
Acceso en línea:	https://doaj.org/article/de84865d38904a608567a9838f944f11
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spelling	oai:doaj.org-article:de84865d38904a608567a9838f944f112021-12-02T13:18:07ZImpact of bronchiolitis guidelines publication on primary care prescriptions in the Italian pediatric population10.1038/s41533-021-00228-w2055-1010https://doaj.org/article/de84865d38904a608567a9838f944f112021-03-01T00:00:00Zhttps://doi.org/10.1038/s41533-021-00228-whttps://doaj.org/toc/2055-1010Abstract In Italy, two clinical practice guidelines for the diagnosis and treatment of bronchiolitis were published in October 2014 and December 2015. We evaluated prescriptions for bronchiolitis in children aged 0–24 months before (December 2012–December 2014), in between (December 2014–December 2015) and after (December 2015–December 2018) the guidelines publications. Data were retrieved from the Pedianet database; the measured outcomes were prescriptions rates of antibiotics, corticosteroids, β2-agonists, and other respiratory drugs. In 1011 out of 1581 episodes, patients received at least one treatment, with a total of 2003 prescriptions. The rate of treated bronchiolitis decreased from 66% to 57% (p < 0.001) after the publication of the second guideline; the highest reduction was in younger patients (from 57% to 44%, p = 0.013). Overall antibiotic prescriptions rate did not change, with 31.6% of the patients still receiving them. Our results confirm unnecessary non-evidence-based treatments in the primary care setting, with few changes after the guidelines publications.Elisa BarbieriAnna CantaruttiSara CavagnisLuigi CantaruttiEugenio BaraldiCarlo GiaquintoDaniele DonàNature PortfolioarticleDiseases of the respiratory systemRC705-779ENnpj Primary Care Respiratory Medicine, Vol 31, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the respiratory system RC705-779
spellingShingle	Diseases of the respiratory system RC705-779 Elisa Barbieri Anna Cantarutti Sara Cavagnis Luigi Cantarutti Eugenio Baraldi Carlo Giaquinto Daniele Donà Impact of bronchiolitis guidelines publication on primary care prescriptions in the Italian pediatric population
description	Abstract In Italy, two clinical practice guidelines for the diagnosis and treatment of bronchiolitis were published in October 2014 and December 2015. We evaluated prescriptions for bronchiolitis in children aged 0–24 months before (December 2012–December 2014), in between (December 2014–December 2015) and after (December 2015–December 2018) the guidelines publications. Data were retrieved from the Pedianet database; the measured outcomes were prescriptions rates of antibiotics, corticosteroids, β2-agonists, and other respiratory drugs. In 1011 out of 1581 episodes, patients received at least one treatment, with a total of 2003 prescriptions. The rate of treated bronchiolitis decreased from 66% to 57% (p < 0.001) after the publication of the second guideline; the highest reduction was in younger patients (from 57% to 44%, p = 0.013). Overall antibiotic prescriptions rate did not change, with 31.6% of the patients still receiving them. Our results confirm unnecessary non-evidence-based treatments in the primary care setting, with few changes after the guidelines publications.
format	article
author	Elisa Barbieri Anna Cantarutti Sara Cavagnis Luigi Cantarutti Eugenio Baraldi Carlo Giaquinto Daniele Donà
author_facet	Elisa Barbieri Anna Cantarutti Sara Cavagnis Luigi Cantarutti Eugenio Baraldi Carlo Giaquinto Daniele Donà
author_sort	Elisa Barbieri
title	Impact of bronchiolitis guidelines publication on primary care prescriptions in the Italian pediatric population
title_short	Impact of bronchiolitis guidelines publication on primary care prescriptions in the Italian pediatric population
title_full	Impact of bronchiolitis guidelines publication on primary care prescriptions in the Italian pediatric population
title_fullStr	Impact of bronchiolitis guidelines publication on primary care prescriptions in the Italian pediatric population
title_full_unstemmed	Impact of bronchiolitis guidelines publication on primary care prescriptions in the Italian pediatric population
title_sort	impact of bronchiolitis guidelines publication on primary care prescriptions in the italian pediatric population
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/de84865d38904a608567a9838f944f11
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Impact of bronchiolitis guidelines publication on primary care prescriptions in the Italian pediatric population

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