Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues

Lactobacillus associates with vaginal protection from HIV-1 infection. Here, the authors show that lactobacilli extracellular vesicles contain bacterial proteins and metabolites that inhibit HIV-1 infection in T cells and in human cervico-vaginal and tonsillar tissues ex vivo via altering viral Env...

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Autores principales:	Rogers A. Ñahui Palomino, Christophe Vanpouille, Luca Laghi, Carola Parolin, Kamran Melikov, Peter Backlund, Beatrice Vitali, Leonid Margolis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/de98294add514f1d93ee457111f3c3d0
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spelling	oai:doaj.org-article:de98294add514f1d93ee457111f3c3d02021-12-02T16:57:55ZExtracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues10.1038/s41467-019-13468-92041-1723https://doaj.org/article/de98294add514f1d93ee457111f3c3d02019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13468-9https://doaj.org/toc/2041-1723Lactobacillus associates with vaginal protection from HIV-1 infection. Here, the authors show that lactobacilli extracellular vesicles contain bacterial proteins and metabolites that inhibit HIV-1 infection in T cells and in human cervico-vaginal and tonsillar tissues ex vivo via altering viral Env proteins.Rogers A. Ñahui PalominoChristophe VanpouilleLuca LaghiCarola ParolinKamran MelikovPeter BacklundBeatrice VitaliLeonid MargolisNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rogers A. Ñahui Palomino Christophe Vanpouille Luca Laghi Carola Parolin Kamran Melikov Peter Backlund Beatrice Vitali Leonid Margolis Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues
description	Lactobacillus associates with vaginal protection from HIV-1 infection. Here, the authors show that lactobacilli extracellular vesicles contain bacterial proteins and metabolites that inhibit HIV-1 infection in T cells and in human cervico-vaginal and tonsillar tissues ex vivo via altering viral Env proteins.
format	article
author	Rogers A. Ñahui Palomino Christophe Vanpouille Luca Laghi Carola Parolin Kamran Melikov Peter Backlund Beatrice Vitali Leonid Margolis
author_facet	Rogers A. Ñahui Palomino Christophe Vanpouille Luca Laghi Carola Parolin Kamran Melikov Peter Backlund Beatrice Vitali Leonid Margolis
author_sort	Rogers A. Ñahui Palomino
title	Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues
title_short	Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues
title_full	Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues
title_fullStr	Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues
title_full_unstemmed	Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues
title_sort	extracellular vesicles from symbiotic vaginal lactobacilli inhibit hiv-1 infection of human tissues
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/de98294add514f1d93ee457111f3c3d0
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Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues

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