Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity

Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity

Steviol glycosides are sweet-tasting compounds isolated from a South American shrub and are increasingly used as sweeteners in foods and beverages. Philippaertet al. demonstrate that steviol glycosides potentiate Ca2+-dependent TRPM5 activity and promote glucose-induced insulin secretion and glucose...

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Autores principales: Koenraad Philippaert, Andy Pironet, Margot Mesuere, William Sones, Laura Vermeiren, Sara Kerselaers, Sílvia Pinto, Andrei Segal, Nancy Antoine, Conny Gysemans, Jos Laureys, Katleen Lemaire, Patrick Gilon, Eva Cuypers, Jan Tytgat, Chantal Mathieu, Frans Schuit, Patrik Rorsman, Karel Talavera, Thomas Voets, Rudi Vennekens
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/de9c509d79484c4cbf19eed74ada6127
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spelling oai:doaj.org-article:de9c509d79484c4cbf19eed74ada61272021-12-02T17:06:18ZSteviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity10.1038/ncomms147332041-1723https://doaj.org/article/de9c509d79484c4cbf19eed74ada61272017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14733https://doaj.org/toc/2041-1723Steviol glycosides are sweet-tasting compounds isolated from a South American shrub and are increasingly used as sweeteners in foods and beverages. Philippaertet al. demonstrate that steviol glycosides potentiate Ca2+-dependent TRPM5 activity and promote glucose-induced insulin secretion and glucose tolerance.Koenraad PhilippaertAndy PironetMargot MesuereWilliam SonesLaura VermeirenSara KerselaersSílvia PintoAndrei SegalNancy AntoineConny GysemansJos LaureysKatleen LemairePatrick GilonEva CuypersJan TytgatChantal MathieuFrans SchuitPatrik RorsmanKarel TalaveraThomas VoetsRudi VennekensNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Koenraad Philippaert
Andy Pironet
Margot Mesuere
William Sones
Laura Vermeiren
Sara Kerselaers
Sílvia Pinto
Andrei Segal
Nancy Antoine
Conny Gysemans
Jos Laureys
Katleen Lemaire
Patrick Gilon
Eva Cuypers
Jan Tytgat
Chantal Mathieu
Frans Schuit
Patrik Rorsman
Karel Talavera
Thomas Voets
Rudi Vennekens
Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity
description Steviol glycosides are sweet-tasting compounds isolated from a South American shrub and are increasingly used as sweeteners in foods and beverages. Philippaertet al. demonstrate that steviol glycosides potentiate Ca2+-dependent TRPM5 activity and promote glucose-induced insulin secretion and glucose tolerance.
format article
author Koenraad Philippaert
Andy Pironet
Margot Mesuere
William Sones
Laura Vermeiren
Sara Kerselaers
Sílvia Pinto
Andrei Segal
Nancy Antoine
Conny Gysemans
Jos Laureys
Katleen Lemaire
Patrick Gilon
Eva Cuypers
Jan Tytgat
Chantal Mathieu
Frans Schuit
Patrik Rorsman
Karel Talavera
Thomas Voets
Rudi Vennekens
author_facet Koenraad Philippaert
Andy Pironet
Margot Mesuere
William Sones
Laura Vermeiren
Sara Kerselaers
Sílvia Pinto
Andrei Segal
Nancy Antoine
Conny Gysemans
Jos Laureys
Katleen Lemaire
Patrick Gilon
Eva Cuypers
Jan Tytgat
Chantal Mathieu
Frans Schuit
Patrik Rorsman
Karel Talavera
Thomas Voets
Rudi Vennekens
author_sort Koenraad Philippaert
title Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity
title_short Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity
title_full Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity
title_fullStr Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity
title_full_unstemmed Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity
title_sort steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of trpm5 channel activity
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/de9c509d79484c4cbf19eed74ada6127
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