On the value of intra-motif dependencies of human insulator protein CTCF.

The binding affinity of DNA-binding proteins such as transcription factors is mainly determined by the base composition of the corresponding binding site on the DNA strand. Most proteins do not bind only a single sequence, but rather a set of sequences, which may be modeled by a sequence motif. Algo...

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Autores principales: Ralf Eggeling, André Gohr, Jens Keilwagen, Michaela Mohr, Stefan Posch, Andrew D Smith, Ivo Grosse
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/de9f98e2c7434908ae45c71a18e090e9
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