Cost-Effectiveness of the COVID-19 Test, Trace and Isolate Program in Colombia

Summary: Background: During the COVID-19 pandemic, Test-Trace-Isolate (TTI) programs have been recommended as a risk mitigation strategy. However, many governments have hesitated to implement them due to their costs. This study aims to estimate the cost-effectiveness of implementing a national TTI...

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Autores principales:	Yenny Guzmán Ruiz, Andres I. Vecino-Ortiz, Nicolás Guzman-Tordecilla, Rolando Enrique Peñaloza-Quintero, Julián A. Fernández-Niño, Maylen Rojas-Botero, Fernando Ruiz Gomez, Sean D. Sullivan, Antonio J. Trujillo
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	Test-Trace-Isolate (TTI) Cost-effectiveness analysis COVID-19 risk assessment and mitigation Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/deaa277dc3314c099ee23ec1b567a693
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spelling	oai:doaj.org-article:deaa277dc3314c099ee23ec1b567a6932021-12-04T04:36:43ZCost-Effectiveness of the COVID-19 Test, Trace and Isolate Program in Colombia2667-193X10.1016/j.lana.2021.100109https://doaj.org/article/deaa277dc3314c099ee23ec1b567a6932022-02-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2667193X21001058https://doaj.org/toc/2667-193XSummary: Background: During the COVID-19 pandemic, Test-Trace-Isolate (TTI) programs have been recommended as a risk mitigation strategy. However, many governments have hesitated to implement them due to their costs. This study aims to estimate the cost-effectiveness of implementing a national TTI program to reduce the number of severe and fatal cases of COVID-19 in Colombia. Methods: We developed a Markov simulation model of COVID-19 infection combined with a Susceptible-Infected-Recovered structure. We estimated the incremental cost-effectiveness of a comprehensive TTI strategy compared to no intervention over a one-year horizon, from both the health system and the societal perspective. Hospitalization and mortality rates were retrieved from Colombian surveillance data. We included program costs of TTI intervention, health services utilization, PCR diagnosis test, productivity loss, and government social program costs. We used the number of deaths and quality-adjusted life years (QALYs) as health outcomes. Sensitivity analyses were performed. Findings: Compared with no intervention, the TTI strategy reduces COVID-19 mortality by 67%. In addition, the program saves an average of $1,045 and $850 per case when observed from the social and the health system perspective, respectively. These savings are equivalent to two times the current health expenditures in Colombia per year. Interpretation: The TTI program is a highly cost-effective public health intervention to reduce the burden of COVID-19 in Colombia. TTI programs depend on their successful and speedy implementation. Funding: This study was supported by the Colombian Ministry of Health through award number PUJ-04519-20 received by EPQ AVO and SDS declined to receive any funding support for this study. The contents are the responsibility of all the individual authors.Yenny Guzmán RuizAndres I. Vecino-OrtizNicolás Guzman-TordecillaRolando Enrique Peñaloza-QuinteroJulián A. Fernández-NiñoMaylen Rojas-BoteroFernando Ruiz GomezSean D. SullivanAntonio J. TrujilloElsevierarticleTest-Trace-Isolate (TTI)Cost-effectiveness analysisCOVID-19risk assessment and mitigationPublic aspects of medicineRA1-1270ENThe Lancet Regional Health. Americas, Vol 6, Iss , Pp 100109- (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Test-Trace-Isolate (TTI) Cost-effectiveness analysis COVID-19 risk assessment and mitigation Public aspects of medicine RA1-1270
spellingShingle	Test-Trace-Isolate (TTI) Cost-effectiveness analysis COVID-19 risk assessment and mitigation Public aspects of medicine RA1-1270 Yenny Guzmán Ruiz Andres I. Vecino-Ortiz Nicolás Guzman-Tordecilla Rolando Enrique Peñaloza-Quintero Julián A. Fernández-Niño Maylen Rojas-Botero Fernando Ruiz Gomez Sean D. Sullivan Antonio J. Trujillo Cost-Effectiveness of the COVID-19 Test, Trace and Isolate Program in Colombia
description	Summary: Background: During the COVID-19 pandemic, Test-Trace-Isolate (TTI) programs have been recommended as a risk mitigation strategy. However, many governments have hesitated to implement them due to their costs. This study aims to estimate the cost-effectiveness of implementing a national TTI program to reduce the number of severe and fatal cases of COVID-19 in Colombia. Methods: We developed a Markov simulation model of COVID-19 infection combined with a Susceptible-Infected-Recovered structure. We estimated the incremental cost-effectiveness of a comprehensive TTI strategy compared to no intervention over a one-year horizon, from both the health system and the societal perspective. Hospitalization and mortality rates were retrieved from Colombian surveillance data. We included program costs of TTI intervention, health services utilization, PCR diagnosis test, productivity loss, and government social program costs. We used the number of deaths and quality-adjusted life years (QALYs) as health outcomes. Sensitivity analyses were performed. Findings: Compared with no intervention, the TTI strategy reduces COVID-19 mortality by 67%. In addition, the program saves an average of $1,045 and $850 per case when observed from the social and the health system perspective, respectively. These savings are equivalent to two times the current health expenditures in Colombia per year. Interpretation: The TTI program is a highly cost-effective public health intervention to reduce the burden of COVID-19 in Colombia. TTI programs depend on their successful and speedy implementation. Funding: This study was supported by the Colombian Ministry of Health through award number PUJ-04519-20 received by EPQ AVO and SDS declined to receive any funding support for this study. The contents are the responsibility of all the individual authors.
format	article
author	Yenny Guzmán Ruiz Andres I. Vecino-Ortiz Nicolás Guzman-Tordecilla Rolando Enrique Peñaloza-Quintero Julián A. Fernández-Niño Maylen Rojas-Botero Fernando Ruiz Gomez Sean D. Sullivan Antonio J. Trujillo
author_facet	Yenny Guzmán Ruiz Andres I. Vecino-Ortiz Nicolás Guzman-Tordecilla Rolando Enrique Peñaloza-Quintero Julián A. Fernández-Niño Maylen Rojas-Botero Fernando Ruiz Gomez Sean D. Sullivan Antonio J. Trujillo
author_sort	Yenny Guzmán Ruiz
title	Cost-Effectiveness of the COVID-19 Test, Trace and Isolate Program in Colombia
title_short	Cost-Effectiveness of the COVID-19 Test, Trace and Isolate Program in Colombia
title_full	Cost-Effectiveness of the COVID-19 Test, Trace and Isolate Program in Colombia
title_fullStr	Cost-Effectiveness of the COVID-19 Test, Trace and Isolate Program in Colombia
title_full_unstemmed	Cost-Effectiveness of the COVID-19 Test, Trace and Isolate Program in Colombia
title_sort	cost-effectiveness of the covid-19 test, trace and isolate program in colombia
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/deaa277dc3314c099ee23ec1b567a693
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Cost-Effectiveness of the COVID-19 Test, Trace and Isolate Program in Colombia

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