$Analysis of the Refractive Profile of Children with Oculocutaneous Albinism versus an Age-Matched Non-Albino Group$
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Analysis of the Refractive Profile of Children with Oculocutaneous Albinism versus an Age-Matched Non-Albino Group

Khulood Muhammad Sayed, Marwa Mahmoud Abdellah, Ahmad Gad Kamel The Department of Ophthalmology, Sohag Faculty of Medicine, Sohag University, Sohag, EgyptCorrespondence: Marwa Mahmoud AbdellahThe Department of Ophthalmology, Sohag Faculty of Medicine, Sohag University, Sohag 82524, EgyptTel +2010071...

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Autores principales:	Sayed KM, Abdellah MM, Kamel AG
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	refractive error albinism young children autorefractometer non albinos Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/deae8a0f18714fc99cad7e3fa2604eec
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spelling	oai:doaj.org-article:deae8a0f18714fc99cad7e3fa2604eec2021-12-02T10:41:27ZAnalysis of the Refractive Profile of Children with Oculocutaneous Albinism versus an Age-Matched Non-Albino Group1177-5483https://doaj.org/article/deae8a0f18714fc99cad7e3fa2604eec2021-01-01T00:00:00Zhttps://www.dovepress.com/analysis-of-the-refractive-profile-of-children-with-oculocutaneous-alb-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Khulood Muhammad Sayed, Marwa Mahmoud Abdellah, Ahmad Gad Kamel The Department of Ophthalmology, Sohag Faculty of Medicine, Sohag University, Sohag, EgyptCorrespondence: Marwa Mahmoud AbdellahThe Department of Ophthalmology, Sohag Faculty of Medicine, Sohag University, Sohag 82524, EgyptTel +2010071291010Email MarwamahmoudAbdellah@yahoo.comPurpose: To find out and analyze the points of difference in the refractive profile between children with complete oculocutaneous albinism (OCA) and an age-matched, non-albino group seeking paediatric ophthalmic examination.Methods: A cross-sectional study was conducted on 164 infants and young children in Paediatric Ophthalmology Center, Sohag City, Egypt. Informed consent was obtained from the participants’ guardians. The study divided the population into 2 equal groups: albino group = 82 eyes, non-albino group = 82 eyes. Cycloplegic refraction and average keratometric measurements using the hand-held autokeratometer were taken for the study groups.Results: In the albino group, astigmatism and hypermetropia were the most common refractive errors, 100% and 62% respectively, with significant difference between both groups. Mean total (TA), corneal (CA) and lenticular astigmatism (LA) were significantly higher in albino group (P< 0.05). All albino eyes were high astigmats (≥ 1.25 D).Conclusion: This study is novel in being comparative and includes the largest sample size ever reported for albino eyes of infants and children. High WTR astigmatism is the most prevalent refractive error in albinos with an overall bias toward hyperopia, but extreme errors (>− 11.00D myopia or >+10.00D hyperopia) are not common. Albino eyes have a significantly higher degree of LA which compensates for the high CA to decrease the amount of TA. The study emphasizes the importance of refraction examination and visual rehabilitation for OCA children as early as possible to reduce eye morbidity-associated low vision.Keywords: refractive error, albinism, young children, autorefractometer, non-albinosSayed KMAbdellah MMKamel AGDove Medical Pressarticlerefractive erroralbinismyoung childrenautorefractometernon albinosOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 15, Pp 73-78 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	refractive error albinism young children autorefractometer non albinos Ophthalmology RE1-994
spellingShingle	refractive error albinism young children autorefractometer non albinos Ophthalmology RE1-994 Sayed KM Abdellah MM Kamel AG Analysis of the Refractive Profile of Children with Oculocutaneous Albinism versus an Age-Matched Non-Albino Group
description	Khulood Muhammad Sayed, Marwa Mahmoud Abdellah, Ahmad Gad Kamel The Department of Ophthalmology, Sohag Faculty of Medicine, Sohag University, Sohag, EgyptCorrespondence: Marwa Mahmoud AbdellahThe Department of Ophthalmology, Sohag Faculty of Medicine, Sohag University, Sohag 82524, EgyptTel +2010071291010Email MarwamahmoudAbdellah@yahoo.comPurpose: To find out and analyze the points of difference in the refractive profile between children with complete oculocutaneous albinism (OCA) and an age-matched, non-albino group seeking paediatric ophthalmic examination.Methods: A cross-sectional study was conducted on 164 infants and young children in Paediatric Ophthalmology Center, Sohag City, Egypt. Informed consent was obtained from the participants’ guardians. The study divided the population into 2 equal groups: albino group = 82 eyes, non-albino group = 82 eyes. Cycloplegic refraction and average keratometric measurements using the hand-held autokeratometer were taken for the study groups.Results: In the albino group, astigmatism and hypermetropia were the most common refractive errors, 100% and 62% respectively, with significant difference between both groups. Mean total (TA), corneal (CA) and lenticular astigmatism (LA) were significantly higher in albino group (P< 0.05). All albino eyes were high astigmats (≥ 1.25 D).Conclusion: This study is novel in being comparative and includes the largest sample size ever reported for albino eyes of infants and children. High WTR astigmatism is the most prevalent refractive error in albinos with an overall bias toward hyperopia, but extreme errors (>− 11.00D myopia or >+10.00D hyperopia) are not common. Albino eyes have a significantly higher degree of LA which compensates for the high CA to decrease the amount of TA. The study emphasizes the importance of refraction examination and visual rehabilitation for OCA children as early as possible to reduce eye morbidity-associated low vision.Keywords: refractive error, albinism, young children, autorefractometer, non-albinos
format	article
author	Sayed KM Abdellah MM Kamel AG
author_facet	Sayed KM Abdellah MM Kamel AG
author_sort	Sayed KM
title	Analysis of the Refractive Profile of Children with Oculocutaneous Albinism versus an Age-Matched Non-Albino Group
title_short	Analysis of the Refractive Profile of Children with Oculocutaneous Albinism versus an Age-Matched Non-Albino Group
title_full	Analysis of the Refractive Profile of Children with Oculocutaneous Albinism versus an Age-Matched Non-Albino Group
title_fullStr	Analysis of the Refractive Profile of Children with Oculocutaneous Albinism versus an Age-Matched Non-Albino Group
title_full_unstemmed	Analysis of the Refractive Profile of Children with Oculocutaneous Albinism versus an Age-Matched Non-Albino Group
title_sort	analysis of the refractive profile of children with oculocutaneous albinism versus an age-matched non-albino group
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/deae8a0f18714fc99cad7e3fa2604eec
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Analysis of the Refractive Profile of Children with Oculocutaneous Albinism versus an Age-Matched Non-Albino Group

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