Characterization of the Synergistic Effect between Ligands of Opioid and Free Fatty Acid Receptors in the Mouse Model of Colitis

Characterization of the Synergistic Effect between Ligands of Opioid and Free Fatty Acid Receptors in the Mouse Model of Colitis

Background: Recent studies suggest that lipids, including free fatty acids (FFAs), are necessary for proper μ opioid receptor (MOR) binding and that activation of opioid receptors (ORs) improves intestinal inflammation. The objective of the study was to investigate a possible interaction between the...

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Autores principales: Agata Binienda, Adam Makaro, Marcin Talar, Julia B. Krajewska, Aleksandra Tarasiuk, Adrian Bartoszek, Adam Fabisiak, Paula Mosińska, Karolina Niewinna, Katarzyna Dziedziczak, Mikołaj Świerczyński, Radzisław Kordek, Maciej Salaga, Jakub Fichna
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
free fatty acid receptors
lipids
opioid receptor
DAMGO
colitis
Organic chemistry
QD241-441
Acceso en línea:https://doaj.org/article/dec6719a244a4da589acc3de5e7f7370
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