Honokiol crosses BBB and BCSFB, and inhibits brain tumor growth in rat 9L intracerebral gliosarcoma model and human U251 xenograft glioma model.

<h4>Background</h4>Gliosarcoma is one of the most common malignant brain tumors, and anti-angiogenesis is a promising approach for the treatment of gliosarcoma. However, chemotherapy is obstructed by the physical obstacle formed by the blood-brain barrier (BBB) and blood-cerebrospinal fl...

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Autores principales: Xianhuo Wang, Xingmei Duan, Guangli Yang, Xiaoyan Zhang, Linyu Deng, Hao Zheng, Chongyang Deng, Jiaolin Wen, Ning Wang, Cheng Peng, Xia Zhao, Yuquan Wei, Lijuan Chen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/dece1e78bedd4ac4bc8ff29f1753f881
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