Bloody <italic toggle="yes">coli</italic>: a Gene Cocktail in <named-content content-type="genus-species">Escherichia coli</named-content> O104:H4

ABSTRACT A recent study published in mBio [Y. H. Grad et al., mBio 4(1):e00452-12, 2013] indicates that a rapid introgressive evolution has occurred in Escherichia coli O104:H4 by sequential acquisition of foreign genetic material involving pathogenicity traits. O104 genetic promiscuity cannot be re...

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Autores principales:	Fernando Baquero, Raquel Tobes
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2013
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/ded0f6e1a81b4a9faacdf9ef893ce9d7
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spelling	oai:doaj.org-article:ded0f6e1a81b4a9faacdf9ef893ce9d72021-11-15T15:40:25ZBloody <italic toggle="yes">coli</italic>: a Gene Cocktail in <named-content content-type="genus-species">Escherichia coli</named-content> O104:H410.1128/mBio.00066-132150-7511https://doaj.org/article/ded0f6e1a81b4a9faacdf9ef893ce9d72013-03-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00066-13https://doaj.org/toc/2150-7511ABSTRACT A recent study published in mBio [Y. H. Grad et al., mBio 4(1):e00452-12, 2013] indicates that a rapid introgressive evolution has occurred in Escherichia coli O104:H4 by sequential acquisition of foreign genetic material involving pathogenicity traits. O104 genetic promiscuity cannot be readily explained by high population sizes. However, extensive interactions leading to cumulative assemblies of pathogenicity genes might be assured by small K-strategist populations exploiting particular intestinal niches. Next-generation sequencing technologies will be critical to detect particular “gene cocktails” as potentially pathogenic ensembles and to predict the risk of future outbreaks.Fernando BaqueroRaquel TobesAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 4, Iss 1 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Fernando Baquero Raquel Tobes Bloody <italic toggle="yes">coli</italic>: a Gene Cocktail in <named-content content-type="genus-species">Escherichia coli</named-content> O104:H4
description	ABSTRACT A recent study published in mBio [Y. H. Grad et al., mBio 4(1):e00452-12, 2013] indicates that a rapid introgressive evolution has occurred in Escherichia coli O104:H4 by sequential acquisition of foreign genetic material involving pathogenicity traits. O104 genetic promiscuity cannot be readily explained by high population sizes. However, extensive interactions leading to cumulative assemblies of pathogenicity genes might be assured by small K-strategist populations exploiting particular intestinal niches. Next-generation sequencing technologies will be critical to detect particular “gene cocktails” as potentially pathogenic ensembles and to predict the risk of future outbreaks.
format	article
author	Fernando Baquero Raquel Tobes
author_facet	Fernando Baquero Raquel Tobes
author_sort	Fernando Baquero
title	Bloody <italic toggle="yes">coli</italic>: a Gene Cocktail in <named-content content-type="genus-species">Escherichia coli</named-content> O104:H4
title_short	Bloody <italic toggle="yes">coli</italic>: a Gene Cocktail in <named-content content-type="genus-species">Escherichia coli</named-content> O104:H4
title_full	Bloody <italic toggle="yes">coli</italic>: a Gene Cocktail in <named-content content-type="genus-species">Escherichia coli</named-content> O104:H4
title_fullStr	Bloody <italic toggle="yes">coli</italic>: a Gene Cocktail in <named-content content-type="genus-species">Escherichia coli</named-content> O104:H4
title_full_unstemmed	Bloody <italic toggle="yes">coli</italic>: a Gene Cocktail in <named-content content-type="genus-species">Escherichia coli</named-content> O104:H4
title_sort	bloody <italic toggle="yes">coli</italic>: a gene cocktail in <named-content content-type="genus-species">escherichia coli</named-content> o104:h4
publisher	American Society for Microbiology
publishDate	2013
url	https://doaj.org/article/ded0f6e1a81b4a9faacdf9ef893ce9d7
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Bloody <italic toggle="yes">coli</italic>: a Gene Cocktail in <named-content content-type="genus-species">Escherichia coli</named-content> O104:H4

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