Cell fate potentials and switching kinetics uncovered in a classic bistable genetic switch

Bistable switches are a common regulatory motif in cell fate decision-making circuits with two mutually exclusive expression states. Here the authors develop a bistable reporter system and report two additional expression states.

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Autores principales:	Xiaona Fang, Qiong Liu, Christopher Bohrer, Zach Hensel, Wei Han, Jin Wang, Jie Xiao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/def3cb6cc4634a29a337f05dfc6dfe29
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spelling	oai:doaj.org-article:def3cb6cc4634a29a337f05dfc6dfe292021-12-02T15:34:04ZCell fate potentials and switching kinetics uncovered in a classic bistable genetic switch10.1038/s41467-018-05071-12041-1723https://doaj.org/article/def3cb6cc4634a29a337f05dfc6dfe292018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05071-1https://doaj.org/toc/2041-1723Bistable switches are a common regulatory motif in cell fate decision-making circuits with two mutually exclusive expression states. Here the authors develop a bistable reporter system and report two additional expression states.Xiaona FangQiong LiuChristopher BohrerZach HenselWei HanJin WangJie XiaoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiaona Fang Qiong Liu Christopher Bohrer Zach Hensel Wei Han Jin Wang Jie Xiao Cell fate potentials and switching kinetics uncovered in a classic bistable genetic switch
description	Bistable switches are a common regulatory motif in cell fate decision-making circuits with two mutually exclusive expression states. Here the authors develop a bistable reporter system and report two additional expression states.
format	article
author	Xiaona Fang Qiong Liu Christopher Bohrer Zach Hensel Wei Han Jin Wang Jie Xiao
author_facet	Xiaona Fang Qiong Liu Christopher Bohrer Zach Hensel Wei Han Jin Wang Jie Xiao
author_sort	Xiaona Fang
title	Cell fate potentials and switching kinetics uncovered in a classic bistable genetic switch
title_short	Cell fate potentials and switching kinetics uncovered in a classic bistable genetic switch
title_full	Cell fate potentials and switching kinetics uncovered in a classic bistable genetic switch
title_fullStr	Cell fate potentials and switching kinetics uncovered in a classic bistable genetic switch
title_full_unstemmed	Cell fate potentials and switching kinetics uncovered in a classic bistable genetic switch
title_sort	cell fate potentials and switching kinetics uncovered in a classic bistable genetic switch
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/def3cb6cc4634a29a337f05dfc6dfe29
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Cell fate potentials and switching kinetics uncovered in a classic bistable genetic switch

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