Derivation of a Pharmacokinetic Model to Include a Plasma-Derived, von Willebrand Factor-Containing Factor VIII (Koate-DVI) Concentrate and its Low-Dose Use

Derivation of a Pharmacokinetic Model to Include a Plasma-Derived, von Willebrand Factor-Containing Factor VIII (Koate-DVI) Concentrate and its Low-Dose Use

Background Population pharmacokinetics (popPK) has been reliably leveraged to generate individual PK in hemophilia patients. Specific popPK models are suited to predict individual PK under a variety of scenarios that may not be captured by clinical trials, allowing for individualized prophylactic tr...

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Autores principales: Dagmar M. Hajducek, Fitri Primacakti, Novie Chozie, Roser Mir, Alanna McEneny-King, Alfonso Iorio, Andrea Edginton
Formato: article
Lenguaje:EN
Publicado: SAGE Publishing 2021
Materias:
Diseases of the blood and blood-forming organs
RC633-647.5
Acceso en línea:https://doaj.org/article/def7f90629ae409f9a18f4b66c5c71e4
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