Derivation of a Pharmacokinetic Model to Include a Plasma-Derived, von Willebrand Factor-Containing Factor VIII (Koate-DVI) Concentrate and its Low-Dose Use
Background Population pharmacokinetics (popPK) has been reliably leveraged to generate individual PK in hemophilia patients. Specific popPK models are suited to predict individual PK under a variety of scenarios that may not be captured by clinical trials, allowing for individualized prophylactic tr...
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| Main Authors: | , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
SAGE Publishing
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/def7f90629ae409f9a18f4b66c5c71e4 |
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