Rolling uphill: in vivo reacquisition of pluripotency during cranial neural crest differentiation

Conrad Waddington famously used his epigenetic landscape to describe the paths a cell might take during developmental differentiation. In this analogy, the undifferentiated stem cell begins at the highest elevation and proceeds to tumble downward towards its final resting place, representing termina...

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Autores principales: Fanju W. Meng, Patrick J. Murphy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/defecbbb3de94f43a44509e7439a4b62
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