Rolling uphill: in vivo reacquisition of pluripotency during cranial neural crest differentiation

Conrad Waddington famously used his epigenetic landscape to describe the paths a cell might take during developmental differentiation. In this analogy, the undifferentiated stem cell begins at the highest elevation and proceeds to tumble downward towards its final resting place, representing termina...

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Bibliographic Details
Main Authors: Fanju W. Meng, Patrick J. Murphy
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Online Access:https://doaj.org/article/defecbbb3de94f43a44509e7439a4b62
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