Structural variant evolution after telomere crisis
Telomere crisis has been shown to induce chromothripsis and breakage fusion bridge (BFB) cycles in vitro. Here, the authors show that telomere crisis generates a much broader spectrum of structural variations, implying that cancers without chromothripsis and BFB cycles could have emerged from telome...
Guardado en:
Autores principales: | Sally M. Dewhurst, Xiaotong Yao, Joel Rosiene, Huasong Tian, Julie Behr, Nazario Bosco, Kaori K. Takai, Titia de Lange, Marcin Imieliński |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/df07fee0b7114bef9405a63b5e335004 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Association between genetic variants in DNA and histone methylation and telomere length.
por: Sangmi Kim, et al.
Publicado: (2012) -
Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population
por: Xuling Chang, et al.
Publicado: (2021) -
Telomeric RNAs are essential to maintain telomeres
por: Juan José Montero, et al.
Publicado: (2016) -
Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening
por: Ryan M. Baxley, et al.
Publicado: (2021) -
Telomere-to-telomere gapless chromosomes of banana using nanopore sequencing
por: Caroline Belser, et al.
Publicado: (2021)