Amino Acid Differences in the 1753-to-1851 Region of TcdB Influence Variations in TcdB1 and TcdB2 Cell Entry

ABSTRACT Clostridium difficile TcdB2 enters cells with a higher efficiency than TcdB1 and exhibits an overall higher level of toxicity. However, the TcdB2-specific sequences that account for more efficient cell entry have not been reported. In this study, we examined the contribution of carboxy-term...

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Bibliographic Details
Main Authors: Jonathan J. Hunt, Jason L. Larabee, Jimmy D. Ballard
Format: article
Language:EN
Published: American Society for Microbiology 2017
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Online Access:https://doaj.org/article/df14dd59e50e4d2db5d147652b5f8dc6
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