Feasibility of using organosilane dry-coated detoxified quartzes as raw material in different industrial sectors

Respirable crystalline silica (RCS), in the form of quartz and cristobalite from occupational sources, was classified by the International Agency for Research on Cancer (IARC) as carcinogenic to humans (category 1). In addition, RCS has recently been included in the Directive (EU) 2017/2398 about ca...

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Autores principales:	E. Monfort, A. López-Lilao, M.J. Ibáñez, C. Ziemann, O. Creutzenberg, G. Bonvicini
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Respirable crystalline silica Silanol groups Quartz coating Organosilane Silicosis Lung cancer Renewable energy sources TJ807-830 Environmental engineering TA170-171
Acceso en línea:	https://doaj.org/article/df17eac604414cf6bd2ec178bbeb9907
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spelling	oai:doaj.org-article:df17eac604414cf6bd2ec178bbeb99072021-11-18T04:52:40ZFeasibility of using organosilane dry-coated detoxified quartzes as raw material in different industrial sectors2666-790810.1016/j.clet.2021.100331https://doaj.org/article/df17eac604414cf6bd2ec178bbeb99072021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2666790821002913https://doaj.org/toc/2666-7908Respirable crystalline silica (RCS), in the form of quartz and cristobalite from occupational sources, was classified by the International Agency for Research on Cancer (IARC) as carcinogenic to humans (category 1). In addition, RCS has recently been included in the Directive (EU) 2017/2398 about carcinogens and mutagens at work. Numerous studies suggest that the toxicity of quartz is conditioned by density and distribution of surface silanol groups, and it has been widely demonstrated at lab scale that masking these silanol groups significantly reduces silica toxicity. Based on these findings, a detoxifying, wet-coating method, using organosilanes as coating agent for reactive surface silanols, was previously developed and tested at industrial scale. In the present work, a new dry-coating process (patent pending) also using organosilanes was developed and applied to detoxify quartzes from different industrial branches. Dry-coating efficiency and stability were assessed and confirmed by both in-vitro tests (lactate dehydrogenase release and alkaline comet assay) and an intratracheal instillation study in rats. Finally, industrial trials were performed by different quartz end users (elastomers, foundry, adhesives, pigments and glazes) to evaluate the technical and economic feasibility of implementing this dry-coating process at industrial scale. From the obtained results, it can be drawn that the proposed methodology seems to represent a promising strategy to significantly reduce the risk associated with the handling of RCS-bearing materials. This RCS coating approach shows enough flexibility to be adapted to different industrial processes without significantly interfering with product quality.E. MonfortA. López-LilaoM.J. IbáñezC. ZiemannO. CreutzenbergG. BonviciniElsevierarticleRespirable crystalline silicaSilanol groupsQuartz coatingOrganosilaneSilicosisLung cancerRenewable energy sourcesTJ807-830Environmental engineeringTA170-171ENCleaner Engineering and Technology, Vol 5, Iss , Pp 100331- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Respirable crystalline silica Silanol groups Quartz coating Organosilane Silicosis Lung cancer Renewable energy sources TJ807-830 Environmental engineering TA170-171
spellingShingle	Respirable crystalline silica Silanol groups Quartz coating Organosilane Silicosis Lung cancer Renewable energy sources TJ807-830 Environmental engineering TA170-171 E. Monfort A. López-Lilao M.J. Ibáñez C. Ziemann O. Creutzenberg G. Bonvicini Feasibility of using organosilane dry-coated detoxified quartzes as raw material in different industrial sectors
description	Respirable crystalline silica (RCS), in the form of quartz and cristobalite from occupational sources, was classified by the International Agency for Research on Cancer (IARC) as carcinogenic to humans (category 1). In addition, RCS has recently been included in the Directive (EU) 2017/2398 about carcinogens and mutagens at work. Numerous studies suggest that the toxicity of quartz is conditioned by density and distribution of surface silanol groups, and it has been widely demonstrated at lab scale that masking these silanol groups significantly reduces silica toxicity. Based on these findings, a detoxifying, wet-coating method, using organosilanes as coating agent for reactive surface silanols, was previously developed and tested at industrial scale. In the present work, a new dry-coating process (patent pending) also using organosilanes was developed and applied to detoxify quartzes from different industrial branches. Dry-coating efficiency and stability were assessed and confirmed by both in-vitro tests (lactate dehydrogenase release and alkaline comet assay) and an intratracheal instillation study in rats. Finally, industrial trials were performed by different quartz end users (elastomers, foundry, adhesives, pigments and glazes) to evaluate the technical and economic feasibility of implementing this dry-coating process at industrial scale. From the obtained results, it can be drawn that the proposed methodology seems to represent a promising strategy to significantly reduce the risk associated with the handling of RCS-bearing materials. This RCS coating approach shows enough flexibility to be adapted to different industrial processes without significantly interfering with product quality.
format	article
author	E. Monfort A. López-Lilao M.J. Ibáñez C. Ziemann O. Creutzenberg G. Bonvicini
author_facet	E. Monfort A. López-Lilao M.J. Ibáñez C. Ziemann O. Creutzenberg G. Bonvicini
author_sort	E. Monfort
title	Feasibility of using organosilane dry-coated detoxified quartzes as raw material in different industrial sectors
title_short	Feasibility of using organosilane dry-coated detoxified quartzes as raw material in different industrial sectors
title_full	Feasibility of using organosilane dry-coated detoxified quartzes as raw material in different industrial sectors
title_fullStr	Feasibility of using organosilane dry-coated detoxified quartzes as raw material in different industrial sectors
title_full_unstemmed	Feasibility of using organosilane dry-coated detoxified quartzes as raw material in different industrial sectors
title_sort	feasibility of using organosilane dry-coated detoxified quartzes as raw material in different industrial sectors
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/df17eac604414cf6bd2ec178bbeb9907
work_keys_str_mv	AT emonfort feasibilityofusingorganosilanedrycoateddetoxifiedquartzesasrawmaterialindifferentindustrialsectors AT alopezlilao feasibilityofusingorganosilanedrycoateddetoxifiedquartzesasrawmaterialindifferentindustrialsectors AT mjibanez feasibilityofusingorganosilanedrycoateddetoxifiedquartzesasrawmaterialindifferentindustrialsectors AT cziemann feasibilityofusingorganosilanedrycoateddetoxifiedquartzesasrawmaterialindifferentindustrialsectors AT ocreutzenberg feasibilityofusingorganosilanedrycoateddetoxifiedquartzesasrawmaterialindifferentindustrialsectors AT gbonvicini feasibilityofusingorganosilanedrycoateddetoxifiedquartzesasrawmaterialindifferentindustrialsectors
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Feasibility of using organosilane dry-coated detoxified quartzes as raw material in different industrial sectors

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