Homeostasis of the ER redox state subsequent to proteasome inhibition
Abstract Endoplasmic reticulum (ER) maintains within, an oxidative redox state suitable for disulfide bond formation. We monitored the ER redox dynamics subsequent to proteasome inhibition using an ER redox probe ERroGFP S4. Proteasomal inhibition initially led to oxidation of the ER, but gradually...
Guardado en:
Autores principales: | Yuki Oku, Masahiro Kariya, Takaaki Fujimura, Jun Hoseki, Yasuyoshi Sakai |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/df1b35d163c24cf2ac5874699cdd79ea |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Multistability maintains redox homeostasis in human cells
por: Jo‐Hsi Huang, et al.
Publicado: (2021) -
Regulation of energy homeostasis by the ubiquitin-independent REGγ proteasome
por: Lianhui Sun, et al.
Publicado: (2016) -
Quantitative phosphoproteomics of proteasome inhibition in multiple myeloma cells.
por: Feng Ge, et al.
Publicado: (2010) -
Inhibition of Sp1 prevents ER homeostasis and causes cell death by lysosomal membrane permeabilization in pancreatic cancer
por: Patricia Dauer, et al.
Publicado: (2017) -
Alterations in glutathione redox homeostasis among adolescents with obesity and anemia
por: Dalal Alkazemi, et al.
Publicado: (2021)