Distribution of bacterial keratitis and emerging resistance to antibiotics in China from 2001 to 2004

Chen Zhang, Yanchuang Liang, Shijing Deng, Zhiqun Wang, Ran Li, Xuguang SunDepartment of Ocular Microbiology, Beijing Institute of Ophthalmology, Beijing Tongren hospital, Capital University of Medical Science, BeijingObjective: To study on the distribution of bacterial keratitis isolates and the re...

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Autores principales:	Chen Zhang, Yanchuang Liang, Shijing Deng, Zhiqun Wang, Ran Li, Xuguang Sun
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2008
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/df1b98c4ea7646b09d0017eb26136b41
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spelling	oai:doaj.org-article:df1b98c4ea7646b09d0017eb26136b412021-12-02T02:45:52ZDistribution of bacterial keratitis and emerging resistance to antibiotics in China from 2001 to 20041177-54671177-5483https://doaj.org/article/df1b98c4ea7646b09d0017eb26136b412008-10-01T00:00:00Zhttp://www.dovepress.com/distribution-of-bacterial-keratitis-and-emerging-resistance-to-antibio-a2363https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Chen Zhang, Yanchuang Liang, Shijing Deng, Zhiqun Wang, Ran Li, Xuguang SunDepartment of Ocular Microbiology, Beijing Institute of Ophthalmology, Beijing Tongren hospital, Capital University of Medical Science, BeijingObjective: To study on the distribution of bacterial keratitis isolates and the resistance to antibiotics in China from 2001 to 2004.Methods: 1985 specimens from the bacterial keratitis at the Beijing Tong Ren Eye Center were cultured and identified. In vitro susceptibility testing of positive isolates to antibiotics was determined by the Kirby-Bauer disk diffusion method and interpreted according to Clinical and Laboratory Standards Institute.Results: Out of 1985 specimens, 279 were culture positive. The percentage of positive culture was 14.06%. Gram-positive cocci and gram-negative bacilli represented 42.65% (119/270) and 35.13% (98/279) respectively. Pseudomonas sp. was the most common organism (20.07%), followed by Corynebacterium sp. (16.85%) and Staphylococcus epidermidis (13.98%). Resistance to ofloxacin, ciprofloxacin, levofloxacin, and tobramycin was 20.2%, 35.9%, 15.5%, and 29.4% respectively. Gram-negative bacilli showed higher resistance to ciprofloxacin. Staphycoccus sp. revealed significant resistance to ciprofloxacin. Streptococcus sp. showed high resistance to tobramycin. The resistance of isolates from older patients (&ge;60Y) to ciproloxacin, levofloxacin, and tobramycin was higher than that from adult patients (&gt;14 to 59Y).Conclusion: Staphylococcus sp., Pseudomonas sp., and Corynebacterium sp. were the most common bacterial keratitis isolates in China. Attentions should be paid to the increase of the resistance to levofloxacin.Keywords: bacteria keratitis resistance Chen ZhangYanchuang LiangShijing DengZhiqun WangRan LiXuguang SunDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2008, Iss Issue 3, Pp 575-579 (2008)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Chen Zhang Yanchuang Liang Shijing Deng Zhiqun Wang Ran Li Xuguang Sun Distribution of bacterial keratitis and emerging resistance to antibiotics in China from 2001 to 2004
description	Chen Zhang, Yanchuang Liang, Shijing Deng, Zhiqun Wang, Ran Li, Xuguang SunDepartment of Ocular Microbiology, Beijing Institute of Ophthalmology, Beijing Tongren hospital, Capital University of Medical Science, BeijingObjective: To study on the distribution of bacterial keratitis isolates and the resistance to antibiotics in China from 2001 to 2004.Methods: 1985 specimens from the bacterial keratitis at the Beijing Tong Ren Eye Center were cultured and identified. In vitro susceptibility testing of positive isolates to antibiotics was determined by the Kirby-Bauer disk diffusion method and interpreted according to Clinical and Laboratory Standards Institute.Results: Out of 1985 specimens, 279 were culture positive. The percentage of positive culture was 14.06%. Gram-positive cocci and gram-negative bacilli represented 42.65% (119/270) and 35.13% (98/279) respectively. Pseudomonas sp. was the most common organism (20.07%), followed by Corynebacterium sp. (16.85%) and Staphylococcus epidermidis (13.98%). Resistance to ofloxacin, ciprofloxacin, levofloxacin, and tobramycin was 20.2%, 35.9%, 15.5%, and 29.4% respectively. Gram-negative bacilli showed higher resistance to ciprofloxacin. Staphycoccus sp. revealed significant resistance to ciprofloxacin. Streptococcus sp. showed high resistance to tobramycin. The resistance of isolates from older patients (&ge;60Y) to ciproloxacin, levofloxacin, and tobramycin was higher than that from adult patients (&gt;14 to 59Y).Conclusion: Staphylococcus sp., Pseudomonas sp., and Corynebacterium sp. were the most common bacterial keratitis isolates in China. Attentions should be paid to the increase of the resistance to levofloxacin.Keywords: bacteria keratitis resistance
format	article
author	Chen Zhang Yanchuang Liang Shijing Deng Zhiqun Wang Ran Li Xuguang Sun
author_facet	Chen Zhang Yanchuang Liang Shijing Deng Zhiqun Wang Ran Li Xuguang Sun
author_sort	Chen Zhang
title	Distribution of bacterial keratitis and emerging resistance to antibiotics in China from 2001 to 2004
title_short	Distribution of bacterial keratitis and emerging resistance to antibiotics in China from 2001 to 2004
title_full	Distribution of bacterial keratitis and emerging resistance to antibiotics in China from 2001 to 2004
title_fullStr	Distribution of bacterial keratitis and emerging resistance to antibiotics in China from 2001 to 2004
title_full_unstemmed	Distribution of bacterial keratitis and emerging resistance to antibiotics in China from 2001 to 2004
title_sort	distribution of bacterial keratitis and emerging resistance to antibiotics in china from 2001 to 2004
publisher	Dove Medical Press
publishDate	2008
url	https://doaj.org/article/df1b98c4ea7646b09d0017eb26136b41
work_keys_str_mv	AT chenzhang distributionofbacterialkeratitisandemergingresistancetoantibioticsinchinafrom2001to2004 AT yanchuangliang distributionofbacterialkeratitisandemergingresistancetoantibioticsinchinafrom2001to2004 AT shijingdeng distributionofbacterialkeratitisandemergingresistancetoantibioticsinchinafrom2001to2004 AT zhiqunwang distributionofbacterialkeratitisandemergingresistancetoantibioticsinchinafrom2001to2004 AT ranli distributionofbacterialkeratitisandemergingresistancetoantibioticsinchinafrom2001to2004 AT xuguangsun distributionofbacterialkeratitisandemergingresistancetoantibioticsinchinafrom2001to2004
_version_	1718402193057382400

Distribution of bacterial keratitis and emerging resistance to antibiotics in China from 2001 to 2004

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