Annotation of Potential Vaccine Targets and Design of a Multi-Epitope Subunit Vaccine against <i>Yersinia pestis</i> through Reverse Vaccinology and Validation through an Agent-Based Modeling Approach

Annotation of Potential Vaccine Targets and Design of a Multi-Epitope Subunit Vaccine against <i>Yersinia pestis</i> through Reverse Vaccinology and Validation through an Agent-Based Modeling Approach

<i>Yersinia pestis</i> is responsible for plague and major pandemics in Asia and Europe. This bacterium has shown resistance to an array of drugs commonly used for the treatment of plague. Therefore, effective therapeutics measurements, such as designing a vaccine that can effectively an...

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Autores principales: Azaz Ul Haq, Abbas Khan, Jafar Khan, Shamaila Irum, Yasir Waheed, Sajjad Ahmad, N. Nizam-Uddin, Aqel Albutti, Nasib Zaman, Zahid Hussain, Syed Shujait Ali, Muhammad Waseem, Fariha Kanwal, Dong-Qing Wei, Qian Wang
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
<i>Yersinia pestis</i>
vaccine targets
epitope mining
in silico cloning
immune simulation
Medicine
R
Acceso en línea:https://doaj.org/article/df1d889ee75d4af986f027c372b202d5
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