ADAM10 and ADAM17 regulate EGFR, c-Met and TNF RI signalling in liver regeneration and fibrosis

Abstract ADAM10 and ADAM17 are proteases that affect multiple signalling pathways by releasing molecules from the cell surface. As their substrate specificities partially overlaps, we investigated their concurrent role in liver regeneration and fibrosis, using three liver-specific deficient mouse li...

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Auteurs principaux: Olga Zbodakova, Karel Chalupsky, Lenka Sarnova, Petr Kasparek, Marketa Jirouskova, Martin Gregor, Radislav Sedlacek
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/df2cddcbdde34b69ae1e9c24d053e8ad
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