A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol

Some individuals develop antibodies against the polyethylene glycol that is commonly used in therapeutic preparations. Here the authors conduct a GWAS in Han Chinese and find the IGH locus is associated with anti-PEG IgM.

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Autores principales:	Chia-Jung Chang, Chien-Hsiun Chen, Bing-Mae Chen, Yu-Cheng Su, Ying-Ting Chen, Michael S. Hershfield, Ming-Ta Michael Lee, Tian-Lu Cheng, Yuan-Tsong Chen, Steve R. Roffler, Jer-Yuarn Wu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/df2dcbdf3ece4077a9f03be585cdb8d7
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:df2dcbdf3ece4077a9f03be585cdb8d72021-12-02T14:40:46ZA genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol10.1038/s41467-017-00622-42041-1723https://doaj.org/article/df2dcbdf3ece4077a9f03be585cdb8d72017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00622-4https://doaj.org/toc/2041-1723Some individuals develop antibodies against the polyethylene glycol that is commonly used in therapeutic preparations. Here the authors conduct a GWAS in Han Chinese and find the IGH locus is associated with anti-PEG IgM.Chia-Jung ChangChien-Hsiun ChenBing-Mae ChenYu-Cheng SuYing-Ting ChenMichael S. HershfieldMing-Ta Michael LeeTian-Lu ChengYuan-Tsong ChenSteve R. RofflerJer-Yuarn WuNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chia-Jung Chang Chien-Hsiun Chen Bing-Mae Chen Yu-Cheng Su Ying-Ting Chen Michael S. Hershfield Ming-Ta Michael Lee Tian-Lu Cheng Yuan-Tsong Chen Steve R. Roffler Jer-Yuarn Wu A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol
description	Some individuals develop antibodies against the polyethylene glycol that is commonly used in therapeutic preparations. Here the authors conduct a GWAS in Han Chinese and find the IGH locus is associated with anti-PEG IgM.
format	article
author	Chia-Jung Chang Chien-Hsiun Chen Bing-Mae Chen Yu-Cheng Su Ying-Ting Chen Michael S. Hershfield Ming-Ta Michael Lee Tian-Lu Cheng Yuan-Tsong Chen Steve R. Roffler Jer-Yuarn Wu
author_facet	Chia-Jung Chang Chien-Hsiun Chen Bing-Mae Chen Yu-Cheng Su Ying-Ting Chen Michael S. Hershfield Ming-Ta Michael Lee Tian-Lu Cheng Yuan-Tsong Chen Steve R. Roffler Jer-Yuarn Wu
author_sort	Chia-Jung Chang
title	A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol
title_short	A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol
title_full	A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol
title_fullStr	A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol
title_full_unstemmed	A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol
title_sort	genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/df2dcbdf3ece4077a9f03be585cdb8d7
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A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol

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