A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol

A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol

Some individuals develop antibodies against the polyethylene glycol that is commonly used in therapeutic preparations. Here the authors conduct a GWAS in Han Chinese and find the IGH locus is associated with anti-PEG IgM.

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Detalles Bibliográficos
Autores principales: Chia-Jung Chang, Chien-Hsiun Chen, Bing-Mae Chen, Yu-Cheng Su, Ying-Ting Chen, Michael S. Hershfield, Ming-Ta Michael Lee, Tian-Lu Cheng, Yuan-Tsong Chen, Steve R. Roffler, Jer-Yuarn Wu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
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Acceso en línea:https://doaj.org/article/df2dcbdf3ece4077a9f03be585cdb8d7
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