Zyxin-Siah2–Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways
Hippo and TGF-β are crucial signalling pathways involved in the development of various types of tumours. Here, the authors demonstrate that TGF-β can directly regulate Hippo pathway through the stabilization of the scaffold protein Zyxin, which forms a ternary complex with Siah2 and Lats2 promoting...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2016
|
| Subjects: | |
| Online Access: | https://doaj.org/article/df320a3c123e49cb9592da2d8a71e6c8 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|