PUMA: a unified framework for penalized multiple regression analysis of GWAS data.

Penalized Multiple Regression (PMR) can be used to discover novel disease associations in GWAS datasets. In practice, proposed PMR methods have not been able to identify well-supported associations in GWAS that are undetectable by standard association tests and thus these methods are not widely appl...

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Bibliographic Details
Main Authors: Gabriel E Hoffman, Benjamin A Logsdon, Jason G Mezey
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Online Access:https://doaj.org/article/df33d74e86dc45a2bc28814d4c499522
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