Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress

The autophagy receptor p62 mediates the assembly and removal of ubiquitylated protein aggregates by forming p62 bodies. Here, the authors identify an acetylation-dependent mechanism that regulates formation and autophagic clearance of p62 bodies under nutrient-deficient conditions.

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Autores principales:	Zhiyuan You, Wen-Xue Jiang, Ling-Yun Qin, Zhou Gong, Wei Wan, Jin Li, Yusha Wang, Hongtao Zhang, Chao Peng, Tianhua Zhou, Chun Tang, Wei Liu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/df3739c6d5be4f2fb8d8248924f5b8fd
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spelling	oai:doaj.org-article:df3739c6d5be4f2fb8d8248924f5b8fd2021-12-02T14:40:18ZRequirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress10.1038/s41467-019-13718-w2041-1723https://doaj.org/article/df3739c6d5be4f2fb8d8248924f5b8fd2019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13718-whttps://doaj.org/toc/2041-1723The autophagy receptor p62 mediates the assembly and removal of ubiquitylated protein aggregates by forming p62 bodies. Here, the authors identify an acetylation-dependent mechanism that regulates formation and autophagic clearance of p62 bodies under nutrient-deficient conditions.Zhiyuan YouWen-Xue JiangLing-Yun QinZhou GongWei WanJin LiYusha WangHongtao ZhangChao PengTianhua ZhouChun TangWei LiuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhiyuan You Wen-Xue Jiang Ling-Yun Qin Zhou Gong Wei Wan Jin Li Yusha Wang Hongtao Zhang Chao Peng Tianhua Zhou Chun Tang Wei Liu Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress
description	The autophagy receptor p62 mediates the assembly and removal of ubiquitylated protein aggregates by forming p62 bodies. Here, the authors identify an acetylation-dependent mechanism that regulates formation and autophagic clearance of p62 bodies under nutrient-deficient conditions.
format	article
author	Zhiyuan You Wen-Xue Jiang Ling-Yun Qin Zhou Gong Wei Wan Jin Li Yusha Wang Hongtao Zhang Chao Peng Tianhua Zhou Chun Tang Wei Liu
author_facet	Zhiyuan You Wen-Xue Jiang Ling-Yun Qin Zhou Gong Wei Wan Jin Li Yusha Wang Hongtao Zhang Chao Peng Tianhua Zhou Chun Tang Wei Liu
author_sort	Zhiyuan You
title	Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress
title_short	Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress
title_full	Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress
title_fullStr	Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress
title_full_unstemmed	Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress
title_sort	requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/df3739c6d5be4f2fb8d8248924f5b8fd
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Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress

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