Mycobacteria counteract a TLR-mediated nitrosative defense mechanism in a zebrafish infection model.

Mycobacteria counteract a TLR-mediated nitrosative defense mechanism in a zebrafish infection model.

Pulmonary tuberculosis (TB), caused by the intracellular bacterial pathogen Mycobacterium tuberculosis (Mtb), is a major world health problem. The production of reactive nitrogen species (RNS) is a potent cytostatic and cytotoxic defense mechanism against intracellular pathogens. Nevertheless, the p...

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Autores principales: Philip M Elks, Michiel van der Vaart, Vincent van Hensbergen, Esther Schutz, Michael J Redd, Emi Murayama, Herman P Spaink, Annemarie H Meijer
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/df3c36734a6a4d189850266f51994aa3
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