Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine
Innate lymphoid cells (ILC), including natural killer (NK) cells, are important innate immune regulators. Here the authors show that, in human infant intestines, CD103+Eomes+ NK cells are the predominant ILC population, but are replaced gradually by Eomes+ T cells, while NKp44+ NK cells persist in a...
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Nature Portfolio
2019
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oai:doaj.org-article:df407d747ae34b6e86a1aa8b20d600bd2021-12-02T16:57:44ZTissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine10.1038/s41467-018-08267-72041-1723https://doaj.org/article/df407d747ae34b6e86a1aa8b20d600bd2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08267-7https://doaj.org/toc/2041-1723Innate lymphoid cells (ILC), including natural killer (NK) cells, are important innate immune regulators. Here the authors show that, in human infant intestines, CD103+Eomes+ NK cells are the predominant ILC population, but are replaced gradually by Eomes+ T cells, while NKp44+ NK cells persist in adult intestines.Adrian F. SagebielFenja SteinertSebastian LunemannChristian KörnerRenée R. C. E. SchreursMarcus AltfeldDaniel PerezKonrad ReinshagenMadeleine J. BundersNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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Science Q Adrian F. Sagebiel Fenja Steinert Sebastian Lunemann Christian Körner Renée R. C. E. Schreurs Marcus Altfeld Daniel Perez Konrad Reinshagen Madeleine J. Bunders Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine |
description |
Innate lymphoid cells (ILC), including natural killer (NK) cells, are important innate immune regulators. Here the authors show that, in human infant intestines, CD103+Eomes+ NK cells are the predominant ILC population, but are replaced gradually by Eomes+ T cells, while NKp44+ NK cells persist in adult intestines. |
format |
article |
author |
Adrian F. Sagebiel Fenja Steinert Sebastian Lunemann Christian Körner Renée R. C. E. Schreurs Marcus Altfeld Daniel Perez Konrad Reinshagen Madeleine J. Bunders |
author_facet |
Adrian F. Sagebiel Fenja Steinert Sebastian Lunemann Christian Körner Renée R. C. E. Schreurs Marcus Altfeld Daniel Perez Konrad Reinshagen Madeleine J. Bunders |
author_sort |
Adrian F. Sagebiel |
title |
Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine |
title_short |
Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine |
title_full |
Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine |
title_fullStr |
Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine |
title_full_unstemmed |
Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine |
title_sort |
tissue-resident eomes+ nk cells are the major innate lymphoid cell population in human infant intestine |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/df407d747ae34b6e86a1aa8b20d600bd |
work_keys_str_mv |
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