Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine

Innate lymphoid cells (ILC), including natural killer (NK) cells, are important innate immune regulators. Here the authors show that, in human infant intestines, CD103+Eomes+ NK cells are the predominant ILC population, but are replaced gradually by Eomes+ T cells, while NKp44+ NK cells persist in a...

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Autores principales: Adrian F. Sagebiel, Fenja Steinert, Sebastian Lunemann, Christian Körner, Renée R. C. E. Schreurs, Marcus Altfeld, Daniel Perez, Konrad Reinshagen, Madeleine J. Bunders
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/df407d747ae34b6e86a1aa8b20d600bd
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spelling oai:doaj.org-article:df407d747ae34b6e86a1aa8b20d600bd2021-12-02T16:57:44ZTissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine10.1038/s41467-018-08267-72041-1723https://doaj.org/article/df407d747ae34b6e86a1aa8b20d600bd2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08267-7https://doaj.org/toc/2041-1723Innate lymphoid cells (ILC), including natural killer (NK) cells, are important innate immune regulators. Here the authors show that, in human infant intestines, CD103+Eomes+ NK cells are the predominant ILC population, but are replaced gradually by Eomes+ T cells, while NKp44+ NK cells persist in adult intestines.Adrian F. SagebielFenja SteinertSebastian LunemannChristian KörnerRenée R. C. E. SchreursMarcus AltfeldDaniel PerezKonrad ReinshagenMadeleine J. BundersNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Adrian F. Sagebiel
Fenja Steinert
Sebastian Lunemann
Christian Körner
Renée R. C. E. Schreurs
Marcus Altfeld
Daniel Perez
Konrad Reinshagen
Madeleine J. Bunders
Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine
description Innate lymphoid cells (ILC), including natural killer (NK) cells, are important innate immune regulators. Here the authors show that, in human infant intestines, CD103+Eomes+ NK cells are the predominant ILC population, but are replaced gradually by Eomes+ T cells, while NKp44+ NK cells persist in adult intestines.
format article
author Adrian F. Sagebiel
Fenja Steinert
Sebastian Lunemann
Christian Körner
Renée R. C. E. Schreurs
Marcus Altfeld
Daniel Perez
Konrad Reinshagen
Madeleine J. Bunders
author_facet Adrian F. Sagebiel
Fenja Steinert
Sebastian Lunemann
Christian Körner
Renée R. C. E. Schreurs
Marcus Altfeld
Daniel Perez
Konrad Reinshagen
Madeleine J. Bunders
author_sort Adrian F. Sagebiel
title Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine
title_short Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine
title_full Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine
title_fullStr Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine
title_full_unstemmed Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine
title_sort tissue-resident eomes+ nk cells are the major innate lymphoid cell population in human infant intestine
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/df407d747ae34b6e86a1aa8b20d600bd
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