ER stress induces anabolic resistance in muscle cells through PKB-induced blockade of mTORC1.
<h4>Background</h4>Anabolic resistance is the inability to increase protein synthesis in response to an increase in amino acids following a meal. One potential mediator of anabolic resistance is endoplasmic reticulum (ER) stress. The purpose of the present study was to test whether ER st...
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Auteurs principaux: | Louise Deldicque, Luc Bertrand, Amy Patton, Marc Francaux, Keith Baar |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/df42a634e2b24edb93baa00d973584f0 |
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