Connections between Immune-Derived Mediators and Sensory Nerves for Itch Sensation

Although histamine is a well-known itch mediator, histamine H<sub>1</sub>-receptor blockers often lack efficacy in chronic itch. Recent molecular and cellular based studies have shown that non-histaminergic mediators, such as proteases, neuropeptides and cytokines, along with their cogna...

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Bibliographic Details
Main Authors: Sumika Toyama, Mitsutoshi Tominaga, Kenji Takamori
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/df42df9e15f34e7594ca44fe8b8e5149
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