Variability of high-sensitivity cardiac troponin T and I in asymptomatic patients receiving hemodialysis

Abstract Variation of high-sensitivity cardiac troponin I and T (hs-cTn) during hemodialysis has been observed. Observational studies demonstrated the increased incidence of adverse cardiovascular events after long compared to short interdialytic intervals. Therefore, we aimed to compare variation o...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Wanwarang Wongcharoen, Teetad Chombandit, Arintaya Phrommintikul, Kajohnsak Noppakun
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/df42fa87915643fbbe5c23e107ae9368
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:df42fa87915643fbbe5c23e107ae9368
record_format	dspace
spelling	oai:doaj.org-article:df42fa87915643fbbe5c23e107ae93682021-12-02T19:10:21ZVariability of high-sensitivity cardiac troponin T and I in asymptomatic patients receiving hemodialysis10.1038/s41598-021-96658-02045-2322https://doaj.org/article/df42fa87915643fbbe5c23e107ae93682021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-96658-0https://doaj.org/toc/2045-2322Abstract Variation of high-sensitivity cardiac troponin I and T (hs-cTn) during hemodialysis has been observed. Observational studies demonstrated the increased incidence of adverse cardiovascular events after long compared to short interdialytic intervals. Therefore, we aimed to compare variation of hs-cTnI and hs-cTnT before and after hemodialysis and between short and long interdialytic intervals. We enrolled 200 asymptomatic patients receiving regular hemodialysis. The hs-cTnI and hs-cTnT levels were measured before and after hemodialysis on the day after short and long interdialytic intervals. Mean age was 62.3 ± 14.8 years (Male 55.5%). Prevalence of increased hs-cTnI and hs-cTnT was 34.5% and 99.0%, respectively. The median ± interquartile range of hs-cTnT increased significantly after hemodialysis during short and long interdialytic intervals. However, hs-cTnI level did not increase after hemodialysis during short and long intervals. We found that levels of hs-cTnI and T did not differ between short interdialytic and long interdialytic intervals. We demonstrated higher prevalence of elevated hs-cTnT in patients with regular hemodialysis compared to hs-cTnI. The rise of hs-cTnT was observed immediately after hemodialysis but no significant change of hs-cTnI was noted. Accordingly, hs-cTnI may be preferable as a diagnostic marker in patients with suspected acute myocardial infarction than hs-cTnT.Wanwarang WongcharoenTeetad ChombanditArintaya PhrommintikulKajohnsak NoppakunNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Wanwarang Wongcharoen Teetad Chombandit Arintaya Phrommintikul Kajohnsak Noppakun Variability of high-sensitivity cardiac troponin T and I in asymptomatic patients receiving hemodialysis
description	Abstract Variation of high-sensitivity cardiac troponin I and T (hs-cTn) during hemodialysis has been observed. Observational studies demonstrated the increased incidence of adverse cardiovascular events after long compared to short interdialytic intervals. Therefore, we aimed to compare variation of hs-cTnI and hs-cTnT before and after hemodialysis and between short and long interdialytic intervals. We enrolled 200 asymptomatic patients receiving regular hemodialysis. The hs-cTnI and hs-cTnT levels were measured before and after hemodialysis on the day after short and long interdialytic intervals. Mean age was 62.3 ± 14.8 years (Male 55.5%). Prevalence of increased hs-cTnI and hs-cTnT was 34.5% and 99.0%, respectively. The median ± interquartile range of hs-cTnT increased significantly after hemodialysis during short and long interdialytic intervals. However, hs-cTnI level did not increase after hemodialysis during short and long intervals. We found that levels of hs-cTnI and T did not differ between short interdialytic and long interdialytic intervals. We demonstrated higher prevalence of elevated hs-cTnT in patients with regular hemodialysis compared to hs-cTnI. The rise of hs-cTnT was observed immediately after hemodialysis but no significant change of hs-cTnI was noted. Accordingly, hs-cTnI may be preferable as a diagnostic marker in patients with suspected acute myocardial infarction than hs-cTnT.
format	article
author	Wanwarang Wongcharoen Teetad Chombandit Arintaya Phrommintikul Kajohnsak Noppakun
author_facet	Wanwarang Wongcharoen Teetad Chombandit Arintaya Phrommintikul Kajohnsak Noppakun
author_sort	Wanwarang Wongcharoen
title	Variability of high-sensitivity cardiac troponin T and I in asymptomatic patients receiving hemodialysis
title_short	Variability of high-sensitivity cardiac troponin T and I in asymptomatic patients receiving hemodialysis
title_full	Variability of high-sensitivity cardiac troponin T and I in asymptomatic patients receiving hemodialysis
title_fullStr	Variability of high-sensitivity cardiac troponin T and I in asymptomatic patients receiving hemodialysis
title_full_unstemmed	Variability of high-sensitivity cardiac troponin T and I in asymptomatic patients receiving hemodialysis
title_sort	variability of high-sensitivity cardiac troponin t and i in asymptomatic patients receiving hemodialysis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/df42fa87915643fbbe5c23e107ae9368
work_keys_str_mv	AT wanwarangwongcharoen variabilityofhighsensitivitycardiactroponintandiinasymptomaticpatientsreceivinghemodialysis AT teetadchombandit variabilityofhighsensitivitycardiactroponintandiinasymptomaticpatientsreceivinghemodialysis AT arintayaphrommintikul variabilityofhighsensitivitycardiactroponintandiinasymptomaticpatientsreceivinghemodialysis AT kajohnsaknoppakun variabilityofhighsensitivitycardiactroponintandiinasymptomaticpatientsreceivinghemodialysis
_version_	1718377120448643072

Variability of high-sensitivity cardiac troponin T and I in asymptomatic patients receiving hemodialysis

Ejemplares similares