Quantitative structural mechanobiology of platelet-driven blood clot contraction

Blood clot contraction is a cellular (patho)physiological process essential for wound healing, hemostasis, and thrombosis. Here, the authors describe the physical structural mechanism by which platelet filopodia pull “hand-over-hand” on fibrin fibers to compact them into bundled agglomerates.

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Autores principales:	Oleg V. Kim, Rustem I. Litvinov, Mark S. Alber, John W. Weisel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/df430f98264444b08d73fd6114ec0f83
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spelling	oai:doaj.org-article:df430f98264444b08d73fd6114ec0f832021-12-02T14:42:41ZQuantitative structural mechanobiology of platelet-driven blood clot contraction10.1038/s41467-017-00885-x2041-1723https://doaj.org/article/df430f98264444b08d73fd6114ec0f832017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00885-xhttps://doaj.org/toc/2041-1723Blood clot contraction is a cellular (patho)physiological process essential for wound healing, hemostasis, and thrombosis. Here, the authors describe the physical structural mechanism by which platelet filopodia pull “hand-over-hand” on fibrin fibers to compact them into bundled agglomerates.Oleg V. KimRustem I. LitvinovMark S. AlberJohn W. WeiselNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Oleg V. Kim Rustem I. Litvinov Mark S. Alber John W. Weisel Quantitative structural mechanobiology of platelet-driven blood clot contraction
description	Blood clot contraction is a cellular (patho)physiological process essential for wound healing, hemostasis, and thrombosis. Here, the authors describe the physical structural mechanism by which platelet filopodia pull “hand-over-hand” on fibrin fibers to compact them into bundled agglomerates.
format	article
author	Oleg V. Kim Rustem I. Litvinov Mark S. Alber John W. Weisel
author_facet	Oleg V. Kim Rustem I. Litvinov Mark S. Alber John W. Weisel
author_sort	Oleg V. Kim
title	Quantitative structural mechanobiology of platelet-driven blood clot contraction
title_short	Quantitative structural mechanobiology of platelet-driven blood clot contraction
title_full	Quantitative structural mechanobiology of platelet-driven blood clot contraction
title_fullStr	Quantitative structural mechanobiology of platelet-driven blood clot contraction
title_full_unstemmed	Quantitative structural mechanobiology of platelet-driven blood clot contraction
title_sort	quantitative structural mechanobiology of platelet-driven blood clot contraction
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/df430f98264444b08d73fd6114ec0f83
work_keys_str_mv	AT olegvkim quantitativestructuralmechanobiologyofplateletdrivenbloodclotcontraction AT rustemilitvinov quantitativestructuralmechanobiologyofplateletdrivenbloodclotcontraction AT marksalber quantitativestructuralmechanobiologyofplateletdrivenbloodclotcontraction AT johnwweisel quantitativestructuralmechanobiologyofplateletdrivenbloodclotcontraction
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Quantitative structural mechanobiology of platelet-driven blood clot contraction

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